Zegeye Alebachew Ferede, Mekonen Enyew Getaneh, Tamir Tadesse Tarik, Tekeba Berhan, Alemu Tewodros Getaneh, Ali Mohammed Seid, Gonete Almaz Tefera, Kassie Alemneh Tadesse, Wassie Mulugeta, Workneh Belayneh Shetie
Department of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Surgical Nursing, College of Medicine and health sciences, University of Gondar, Gondar, Ethiopia.
Matern Health Neonatol Perinatol. 2025 Apr 3;11(1):10. doi: 10.1186/s40748-025-00205-y.
Stillbirth is one of the biggest adverse pregnancy outcomes in countries with low and middle incomes. If current trends continue, 15.9 million babies will be stillborn; nearly half of these (7.7 million, or 48%) will occur in sub-Saharan Africa. Although stillbirth is one of the health care indicators, its prevalence and determinates are not well studied in low- and middle-income countries (LMIC). Therefore, this study aims to assess the prevalence and associated factors of stillbirth among people at extreme ages of reproductive life in Sub-Saharan Africa.
Data from the most recent Demographic and Health Surveys, which covered 23 Sub-Saharan African countries from 2015 to 2022, were used for secondary data analysis. The study used a total of 76,451 women. STATA 14 was used to analyze the data. The associated factors of stillbirth were determined using a multilevel mixed-effects logistic retrogression model. Significant factors associated with stillbirth were declared significant at p- value < 0.05.
The prevalence of stillbirth in Sub-Saharan Africa was 6.18% (95% CI: 6.01, 6.35). Higher odds of stillbirth were observed among women at advanced age (35-49 years) (AOR = 3.72, 95% CI: 2.57, 5.41), those who consumed alcohol during pregnancy (AOR = 1.58, 95% CI: 1.24, 2.00), and those who underwent cesarean section delivery (AOR = 1.23, 95% CI: 1.11, 1.37). Additionally, rural residence (AOR = 1.11, 95% CI: 1.01, 1.23), high community levels of illiteracy (AOR = 1.19, 95% CI: 1.07, 1.32), and residing in South sub-Saharan Africa (AOR = 1.19, 95% CI: 1.03, 1.38) were positively associated with stillbirth.
This study concludes that stillbirth among women at extreme ages of reproductive life is high compared to the UNICEF 2022 report. The study identified that both individual and community-level variables were associated factors of stillbirth. Therefore, the ministries of health in Sub-Saharan African countries should give attention to those women at the extreme ages of reproductive life and to women from rural areas while designing policies and strategies targeting reducing stillbirth rates.
死产是低收入和中等收入国家最严重的不良妊娠结局之一。如果当前趋势持续下去,将会有1590万婴儿死产;其中近一半(770万,即48%)将发生在撒哈拉以南非洲地区。尽管死产是卫生保健指标之一,但在低收入和中等收入国家,其患病率和决定因素尚未得到充分研究。因此,本研究旨在评估撒哈拉以南非洲地区生殖年龄极端人群中死产的患病率及相关因素。
利用2015年至2022年覆盖23个撒哈拉以南非洲国家的最新人口与健康调查数据进行二次数据分析。该研究共纳入76451名女性。使用STATA 14软件对数据进行分析。采用多水平混合效应逻辑回归模型确定死产的相关因素。与死产相关的显著因素在p值<0.05时被判定为显著。
撒哈拉以南非洲地区的死产患病率为6.18%(95%置信区间:6.01,6.35)。高龄(35 - 49岁)女性(调整后比值比[AOR]=3.72,95%置信区间:2.57,5.41)、孕期饮酒女性(AOR = 1.58,95%置信区间:1.24,2.00)以及剖宫产分娩女性(AOR = 1.23,95%置信区间:1.11,1.37)的死产几率更高。此外,农村居住(AOR = 1.11,95%置信区间:1.01,1.23)、社区文盲率高(AOR = 1.19,95%置信区间:1.07,1.32)以及居住在撒哈拉以南非洲南部地区(AOR = 1.19,95%置信区间:1.03,1.38)与死产呈正相关。
本研究得出结论,与联合国儿童基金会2022年报告相比,生殖年龄极端的女性死产率较高。该研究确定个体和社区层面的变量均为死产的相关因素。因此,撒哈拉以南非洲国家的卫生部在制定降低死产率的政策和策略时,应关注生殖年龄极端的女性以及农村地区的女性。