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化学和生物学方面的最新进展。 (原句表述稍显简略和不规范,推测可能是想表达“Recent advances in chemical and biological aspects.” )

Recent advances of in chemical and biological aspects.

作者信息

Lei Ziqin, Qin Xiaoyan, Yang Yan, Xu Min, Zeng Nan

机构信息

The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiao Tong University, Chengdu, China.

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

出版信息

Front Pharmacol. 2025 Mar 19;16:1492671. doi: 10.3389/fphar.2025.1492671. eCollection 2025.

Abstract

(Turn.) C.Ag. (SP) is a traditional Chinese marine medicinal material known for its extensive pharmacological activities and is primarily found in coastal regions. With a long history of medicinal use in China, it is commonly employed to treat conditions such as goiter, hyperplasia of mammary glands, hypertension, and obesity. Modern research on its phytochemical metabolites has identified polysaccharides, flavonoids, and lipids as the primary metabolites derived from SP, with polysaccharides being the most extensively studied. Modern pharmacological studies have demonstrated that extracts and secondary metabolites obtained from SP exert various biological activities, including antioxidant effects, antitumor properties, hypolipidemic and hypoglycemic actions, antibacterial activity, and immunomodulatory capabilities. This review aims to serve as a theoretical reference for further utilization and development of functional foods derived from marine resources like SP, summarizing relevant literature from both domestic and international sources. Despite a comprehensive overview of chemical metabolites and pharmacological properties, existing limitations suggest the need for more precise technical tools and additional toxicological and clinical studies to ensure quality, safety, and efficacy.

摘要

(翻转。)银柴胡(SP)是一种传统的中国海洋药材,以其广泛的药理活性而闻名,主要分布在沿海地区。在中国有着悠久的药用历史,常用于治疗甲状腺肿、乳腺增生、高血压和肥胖等病症。对其植物化学代谢产物的现代研究已确定多糖、黄酮类化合物和脂质是源自SP的主要代谢产物,其中多糖是研究最为广泛的。现代药理学研究表明,从SP中获得的提取物和次生代谢产物具有多种生物活性,包括抗氧化作用、抗肿瘤特性、降血脂和降血糖作用、抗菌活性以及免疫调节能力。本综述旨在为进一步利用和开发像SP这样的海洋资源衍生的功能性食品提供理论参考,总结国内外相关文献。尽管对化学代谢产物和药理特性进行了全面概述,但现有局限性表明需要更精确的技术工具以及更多的毒理学和临床研究,以确保质量、安全性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf45/11961962/e3aa5ccb113c/fphar-16-1492671-g001.jpg

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