Dorado Caycedo Isabela, López Takegami Juan C H, Rivera Perdomo Eduardo A, González Díaz Claudia P
Department of Dermatology, Fundación Universitaria Sanitas, Bogota, Colombia.
Department of Pathology, Fundación Universitaria Sanitas, Bogota, Colombia.
Skin Appendage Disord. 2025 Apr;11(2):202-206. doi: 10.1159/000541808. Epub 2024 Nov 7.
Eccrine angiomatous hamartoma (EAH) is a benign tumor characterized by the proliferation of eccrine glands and vascular structures. It can be congenital or appear during childhood, with rare cases arising in adults. EAH typically presents as a solitary purplish plaque or nodule but a multifocal presentation in a blaschkoid or segmental distribution has been described.
We report the case of an extensive EAH following the territory of the superficial veins of the lower limbs, arising in an adult diagnosed with venous insufficiency at a young age and that worsened after saphenectomy.
The histopathological and ultrasonographic characteristics suggest that this case may represent a new instance of EAH associated with arteriovenous malformation. We hypothesize that there might be common molecular pathways linking both conditions and that, in predisposed patients, saphenectomy can exacerbate EAH.
小汗腺血管瘤样错构瘤(EAH)是一种良性肿瘤,其特征是小汗腺和血管结构的增生。它可以是先天性的,也可在儿童期出现,成人发病的情况罕见。EAH通常表现为单个紫色斑块或结节,但也有呈线状或节段性分布的多灶性表现的报道。
我们报告一例广泛的EAH病例,其沿着下肢浅静脉分布,发生于一名年轻时被诊断为静脉功能不全且在大隐静脉切除术后病情加重的成年人。
组织病理学和超声特征表明,该病例可能代表与动静脉畸形相关的EAH的一个新病例。我们推测,可能存在连接这两种情况的共同分子途径,并且在易感患者中,大隐静脉切除术可使EAH恶化。