Shin Jaeyoung, Jang Yong Hyun, Kim Soo-Chan, Kim You Chan
Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
Ann Dermatol. 2013 May;25(2):208-12. doi: 10.5021/ad.2013.25.2.208. Epub 2013 May 10.
Eccrine angiomatous hamartoma (EAH) is a rare benign nodular lesion characterized by the proliferation of eccrine and vascular structures, generally capillaries, in the middle and deep dermis. It may be congenital or appear later in childhood, but rarely arises in adulthood.
To investigate the clinicopathologic features of EAH in Korean patients.
Ten cases of EAH diagnosed at Ajou University Hospital and Gangnam Severance Hospital in Korea from 2007 to 2010 were retrospectively reviewed.
The age range of patients was between 5 and 66 years with an equal number of male and female patients. Apart from two congenital cases, the onset was late, ranging from 6 months to 65 years of age. All lesions were solitary and located on the distal extremities. Nine cases appeared as a yellow-brown nodule or plaque resembling a callus. Neither hyperhidrosis nor hypertrichosis was documented. Apart from the typical histological findings of EAH, prominent mucin deposition, fat component and nerve infiltration were observed.
This is one of the largest single case series of EAH in the literature. Clinically, resemblance to callosities and the frequent occurrence in the adulthood were the unique features in our series.
小汗腺血管瘤样错构瘤（EAH）是一种罕见的良性结节性病变，其特征是小汗腺和血管结构（通常为毛细血管）在真皮中层和深层增生。它可能是先天性的，也可能在儿童期后期出现，但在成年期很少发生。
研究韩国患者EAH的临床病理特征。
回顾性分析2007年至2010年在韩国峨山大学医院和江南severance医院诊断的10例EAH病例。
患者年龄范围为5至66岁，男女患者数量相等。除2例先天性病例外，发病较晚，年龄范围为6个月至65岁。所有病变均为单发，位于四肢远端。9例表现为黄褐色结节或斑块，类似胼胝。未记录到多汗症或多毛症。除了EAH的典型组织学表现外，还观察到显著的黏液沉积、脂肪成分和神经浸润。
这是文献中最大的EAH单病例系列之一。在我们的系列中，临床上与胼胝相似以及在成年期频繁发生是独特的特征。
