用于治疗重症社区获得性肺炎的皮质类固醇：一项全英国范围的调查。
Corticosteroids for the management of severe community-acquired pneumonia: A UK-wide survey.
作者信息
Terrington Isis, Cox Olivia, Webb Elizabeth, Eastwood Benjamin, Copley Patrick, Saeed Kordo, Conway Morris Andrew, Grocott Michael Pw, Dushianthan Ahilanandan
机构信息
General Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Department of Infection and Tropical Medicine, Royal Hallamshire Hospital, Sheffield, UK.
出版信息
J Intensive Care Soc. 2025 Mar 31:17511437251330145. doi: 10.1177/17511437251330145.
The use of corticosteroids in severe community-acquired pneumonia (sCAP) management is a contentious issue with current practices of United Kingdom (UK) intensivists largely unknown. To investigate this, we surveyed UK intensive care clinicians from 20 September 2024 to 19 December 2024, collecting 160 responses from 115 intensive care units (response rate 48.3%). 56.1% of responders use corticosteroids in the treatment of sCAP. There were large variabilities in practice. Hydrocortisone started within 24 h of admission 50 mg four times a day for 4-5 days was the most reported regime. The variation in practice coupled with relative equipoise requires further evaluation and guidance.
在严重社区获得性肺炎（sCAP）的治疗中使用皮质类固醇是一个有争议的问题，目前英国重症监护医生的实际做法很大程度上尚不明确。为了对此进行调查，我们在2024年9月20日至2024年12月19日期间对英国重症监护临床医生进行了调查，从115个重症监护病房收集了160份回复（回复率48.3%）。56.1%的受访者在治疗sCAP时使用皮质类固醇。实际做法存在很大差异。最常报告的方案是在入院24小时内开始使用氢化可的松，每天4次，每次50毫克，持续4 - 5天。实际做法的差异以及相对的平衡需要进一步评估和指导。
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