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[F]QTFT, a nicotinate-based radiotracer targeting P2Y with satisfactory blood‒brain barrier (BBB) permeability.

作者信息

Song Ying-Qi, Sheng Chunquan

机构信息

Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.

The Center for Basic Research and Innovation of Medicine and Pharmacy (MOE), School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai 200433, China.

出版信息

Acta Pharm Sin B. 2025 Feb;15(2):1202-1204. doi: 10.1016/j.apsb.2025.02.010. Epub 2025 Mar 11.

DOI:10.1016/j.apsb.2025.02.010
PMID:40177550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959882/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/734b/11959882/cf66a1c632bd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/734b/11959882/cf66a1c632bd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/734b/11959882/cf66a1c632bd/gr1.jpg

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本文引用的文献

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Theranostics. 2024 Sep 30;14(16):6319-6336. doi: 10.7150/thno.97149. eCollection 2024.
2
A Fast-Binding, Functionally Reversible, COX-2 Radiotracer for CNS PET Imaging.一种用于中枢神经系统正电子发射断层显像（PET）成像的快速结合、功能可逆的环氧化酶-2（COX-2）放射性示踪剂。
ACS Cent Sci. 2024 Apr 25;10(5):1105-1114. doi: 10.1021/acscentsci.3c01564. eCollection 2024 May 22.
3
Microglia regulate sleep through calcium-dependent modulation of norepinephrine transmission.
小胶质细胞通过钙依赖性调节去甲肾上腺素传递来调节睡眠。
Nat Neurosci. 2024 Feb;27(2):249-258. doi: 10.1038/s41593-023-01548-5. Epub 2024 Jan 18.
4
Metabolic reprogramming and polarization of microglia in Parkinson's disease: Role of inflammasome and iron.帕金森病中小胶质细胞的代谢重编程和极化：炎性小体和铁的作用。
Ageing Res Rev. 2023 Sep;90:102032. doi: 10.1016/j.arr.2023.102032. Epub 2023 Aug 10.
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P2Y12 receptor gene polymorphisms are associated with epilepsy.P2Y12 受体基因多态性与癫痫有关。
Purinergic Signal. 2023 Mar;19(1):155-162. doi: 10.1007/s11302-022-09848-4. Epub 2022 Feb 17.
6
P2X7 receptor-specific radioligand F-FTTM for atherosclerotic plaque PET imaging.用于动脉粥样硬化斑块 PET 成像的 P2X7 受体特异性放射性配体 F-FTTM。
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