Du Weijia, Qian Xiaozhe, Xu Zhendong, Liu Zhiqiang
Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Front Psychiatry. 2025 Mar 19;16:1511817. doi: 10.3389/fpsyt.2025.1511817. eCollection 2025.
Postpartum depression is a common complication of childbirth that can seriously affect women, infants, and families. In 2020, the National Health Commission of the People's Republic of China mandated depression and anxiety screenings during pregnancy and postpartum visits to ensure timely medical intervention and referrals to appropriate behavioral health resources. Anesthesiologists are indispensable members in obstetric practice. Optimal peripartum pain control can reduce stress response; promote breastfeeding; and lower maternal anxiety and depression. Recently, the discovery of the rapid and sustained antidepressant properties of ketamine and emerging evidence supporting the effectiveness of anesthetic drugs in the treatment of depressive disorders have positioned anesthesiologists on a new frontier for treating neuropsychiatric disorders. This review aimed to explore the impact of labor epidural analgesia, obstetric anesthesia, and anesthetic drugs on postpartum depression while discussing the emerging role of anesthesiologists in its prevention and treatment based on recent evidence.
产后抑郁症是分娩常见的并发症，会严重影响女性、婴儿和家庭。2020年，中华人民共和国国家卫生健康委员会规定在孕期和产后访视时进行抑郁和焦虑筛查，以确保及时进行医疗干预并转介至适当的行为健康资源。麻醉医生是产科医疗团队中不可或缺的成员。围产期疼痛的优化控制可减轻应激反应；促进母乳喂养；并降低产妇的焦虑和抑郁情绪。最近，氯胺酮快速且持续的抗抑郁特性的发现以及支持麻醉药物治疗抑郁症有效性的新证据，使麻醉医生处于治疗神经精神疾病的新前沿。本综述旨在探讨分娩硬膜外镇痛、产科麻醉和麻醉药物对产后抑郁症的影响，同时根据最新证据讨论麻醉医生在其预防和治疗中的新作用。
