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[正常分娩:生理分娩支持与医疗程序。法国国家卫生管理局(HAS)在法国妇产科医生学院(CNGOF)和法国助产士学院(CNSF)合作下制定的指南——产妇福祉与分娩时的区域或全身镇痛]

[Normal childbirth: physiologic labor support and medical procedures. Guidelines of the French National Authority for Health (HAS) with the collaboration of the French College of Gynaecologists and Obstetricians (CNGOF) and the French College of Midwives (CNSF) - Mother's wellbeing and regional or systemic analgesia for labor].

作者信息

Ducloy-Bouthors A-S, Keita-Meyer H, Bouvet L, Bonnin M, Morau E

机构信息

Société française d'anesthésie réanimation, Lille, France; Club d'anesthésie réanimation en obstétrique, Lille, France; Maternité Jeanne-de-Flandre, CHRU de Lille, 59000 Lille, France.

Société française d'anesthésie réanimation, Lille, France; Club d'anesthésie réanimation en obstétrique, Lille, France; Hôpital Louis-Mourrier, Assistance publique des Hôpitaux de Paris, 92700 Colombes, France.

出版信息

Gynecol Obstet Fertil Senol. 2020 Dec;48(12):891-906. doi: 10.1016/j.gofs.2020.09.015. Epub 2020 Oct 1.

Abstract

INTRODUCTION

These guidelines deal with the parturient wellbeing in terms of hydration and regional and systemic pain management during labour.

METHOD

Guidelines were established based on literature analysis and experts consensus.

RESULTS

Clear liquids consumption is permitted all along labor and postpartum, without volume limitation, in patients at low risk of general anesthesia (grade B). The consumption of solid foods is not recommended during the active stage of labor (consensus agreement). It is recommended to promote on regional analgesia to prevent inhalation (grade A). Pain relief using regional analgesia is a part of normal childbirth. It is recommended to provide regional analgesia to parturient who wish these technics. Regional analgesia is the safest and most effective analgesic method for the mother (grade A) and the child (grade B). It is recommended to inform women on the analgesic technics, to respect their choice and consider the right for a parturient to change her strategy in obstetrical circumstances or in cases of untractable pain (consensus agreement). It is recommended to perform a "low-dose" regional analgesia that respects the experience of childbirth (grade A) and maintain it with a patient controlled epidural analgesia technics (grade A). There is no minimum cervical dilation to allow epidural analgesia (grade A). In cases of rapid labor or after delivery for revision, spinal or combined spinal epidural can be used (grade C). Epidural has not to be ended before birth (consensus agreement). Blood pressure and fetal heart rate must be monitored every 3minutes after induction and/or each 10mL bolus then hourly (consensus agreement). Systematic and preventive fluid loading is not needed if only due to regional analgesia (grade B). Deambulation or postures are allowed in the absence of motor block and must be traced and do not alter the distribution of the regional analgesia (grade C). The postures of childbirth do not alter regional analgesia spread (NP2). There is no effect low dose regional analgesia on the duration of obstetric labor, nor the rate of instrumental births or caesarean section (NP1). Systematic use of oxytocin due to epidural analgesia is neither useful nor recommended (AE). Regional analgesia has no side effect on the fetus or newborn (NP1). If regional analgesia is contraindicated or during the waiting time, alternatives analgesic drugs (entonox, nalbuphine and tramadol or pudendal block) can be used but their analgesic efficiency remains mediocre to moderate and they are associated with adverse maternal and especially neonatal side effects (NP2). Remifentanil, ketamine and volatile anesthetics are excluded from these recommendations.

CONCLUSION

The present guidelines were established to update wellbeing of normal parturient during normal labor: hydration is recommended and low dose patient-controlled regional (epidural and spinal) analgesia is the most effective and safest analgesic method.

摘要

引言

本指南涉及分娩期间产妇在补液、区域及全身疼痛管理方面的健康状况。

方法

基于文献分析和专家共识制定指南。

结果

对于全身麻醉低风险患者(B级),分娩全程及产后均可饮用清液,无容量限制。分娩活跃期不建议食用固体食物(达成共识)。建议推广区域镇痛以预防吸入(A级)。使用区域镇痛缓解疼痛是正常分娩的一部分。建议为希望采用这些技术的产妇提供区域镇痛。区域镇痛对母亲(A级)和胎儿(B级)而言是最安全、最有效的镇痛方法。建议告知产妇镇痛技术,尊重她们的选择,并考虑产妇在产科情况或剧痛情况下改变策略的权利(达成共识)。建议实施尊重分娩体验的“低剂量”区域镇痛(A级),并采用患者自控硬膜外镇痛技术维持(A级)。实施硬膜外镇痛无最低宫颈扩张要求(A级)。对于急产或产后修补时,可使用脊髓或联合脊髓硬膜外麻醉(C级)。硬膜外麻醉在胎儿娩出前不得停止(达成共识)。诱导后及/或每推注10mL药物后每3分钟监测一次血压和胎儿心率,随后每小时监测一次(达成共识)。仅因区域镇痛无需进行系统性预防性补液(B级)。在无运动阻滞的情况下允许走动或变换体位,必须进行记录且不得改变区域镇痛的分布(C级)。分娩体位不改变区域镇痛的扩散(NP2)。低剂量区域镇痛对产程、器械助产率或剖宫产率无影响(NP1)。因硬膜外镇痛系统性使用缩宫素既无益处也不推荐(AE)。区域镇痛对胎儿或新生儿无副作用(NP1)。如果区域镇痛禁忌或处于等待期,可使用替代镇痛药物(氧化亚氮、纳布啡、曲马多或阴部阻滞),但其镇痛效果仍为中等至一般,且伴有产妇尤其是新生儿的不良反应(NP2)。本推荐不包括瑞芬太尼、氯胺酮和挥发性麻醉剂。

结论

制定本指南旨在更新正常分娩期间正常产妇的健康状况:建议补液,低剂量患者自控区域(硬膜外和脊髓)镇痛是最有效、最安全的镇痛方法。

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