Shaikh Simran, Panchbudhe Sanjyoti A, Shivkar Rajni R, Banerjee Arnab, Deshmukh Paulami, Kadam Charushila Y
Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.
Department of Physiology (UG & PG), Serampore College, Hooghly, West Bengal, India.
J Basic Clin Physiol Pharmacol. 2025 Apr 4;36(2-3):113-128. doi: 10.1515/jbcpp-2025-0029. eCollection 2025 Mar 1.
Point-of-care testing (POCT) refers to decentralized testing done using complex but compact, portable devices that can be done near the site at the patient's bedside. These enable quick diagnosis and timely intervention because turnaround time (TAT) decreases with these devices. They can also be operated by non-medical personnel and patients with minimum expertise as these devices are easy to handle and interpret. This increases patient awareness regarding their diseases and benefits doctors in giving more patient-centered care. POCT devices require minimum setup and can be utilized even in remote places. The present review focuses on POCT devices employed specifically in clinical biochemistry, e.g., glucose, HbA1c, cardiac biomarkers, fertility tests, hematological analysis, electrolytes, enzymes, urine dipstick tests, etc. This introductory review delves into comprehending the fundamentals of POCT technologies, their guidelines, applications, advantages, and disadvantages. It covers a broad overview of the tests done and the samples required to process these tests. It also compares the pros and cons of POCT devices over centralized laboratory testing. The review also aims to emphasize the relevance of its use in today's era, current trends regarding POCT in urban and rural setups, challenges faced in the field during its implementation, and the potential areas of improvement in the future. However, it is advisable to seek references for more detailed and critical information regarding all the specific topics given in this review article.
即时检验（POCT）是指使用复杂但紧凑、便于携带的设备在患者床边等现场附近进行的分散式检验。这些设备能够实现快速诊断和及时干预，因为使用这些设备时周转时间（TAT）会缩短。由于这些设备易于操作和解读，非医疗人员和专业知识有限的患者也可以操作。这提高了患者对自身疾病的认知，并有利于医生提供更以患者为中心的护理。POCT设备所需的设置最少，即使在偏远地区也能使用。本综述重点关注临床生物化学中专门使用的POCT设备，例如血糖、糖化血红蛋白、心脏生物标志物、生育力检测、血液学分析、电解质、酶、尿试纸检测等。这篇介绍性综述深入探讨了POCT技术的基本原理、其指南、应用、优点和缺点。它涵盖了所进行检测的广泛概述以及处理这些检测所需的样本。它还比较了POCT设备与集中式实验室检测的优缺点。该综述还旨在强调其在当今时代使用的相关性、城乡地区POCT的当前趋势、实施过程中该领域面临的挑战以及未来潜在的改进领域。然而，对于本文中给出的所有具体主题，建议查阅参考文献以获取更详细和关键的信息。
