用于切除性胶质母细胞瘤治疗的可植入装置
Implantable devices for resected glioblastoma therapy.
作者信息
Chang Xiaoyu, Guo Hui, Li Yunqian, Ding Jianxun
机构信息
Department of Neurosurgery, the First Hospital of Jilin University, Changchun 130061, China.
Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
出版信息
Asian J Pharm Sci. 2025 Apr;20(2):101034. doi: 10.1016/j.ajps.2025.101034. Epub 2025 Feb 8.
Glioblastoma (GBM) is a highly infiltrative brain tumor. The treatment of GBM is challenging due to the existence of blood brain barrier, its highly invasive nature, and its heterogeneity. Given the limitations of conventional therapies, this Perspective explores the development trajectory of implantable devices, highlighting the advantages of current models. With the progression in research, these implantable devices certainly hold promising potential for GBM therapy.
胶质母细胞瘤（GBM）是一种具有高度浸润性的脑肿瘤。由于血脑屏障的存在、其高度侵袭性以及异质性，GBM的治疗具有挑战性。鉴于传统疗法的局限性，本观点探讨了可植入设备的发展轨迹，突出了当前模型的优势。随着研究的进展，这些可植入设备在GBM治疗方面肯定具有广阔的潜力。
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