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复杂性直肠尿道瘘修复的尿整形方法:适应证、技术及结果

The Uroplastic Approach to Complex Rectourethral Fistula Repair: Indications, Technique, Results.

作者信息

Brush Erin, Hernandez J Andres, Flusché Ann Marie, Oleck Nicholas C, Naga Hani I, Wickenheisser Victoria, Hayden Joshua P, Mantyh Christopher R, Peterson Andrew C, Erdmann Detlev

机构信息

From the Duke University School of Medicine, Durham, NC.

Department of Surgery, Division of Plastic Surgery, Duke University, Durham, NC.

出版信息

Plast Reconstr Surg Glob Open. 2025 Apr 2;13(4):e6662. doi: 10.1097/GOX.0000000000006662. eCollection 2025 Apr.

DOI:10.1097/GOX.0000000000006662
PMID:40182296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11964384/
Abstract

BACKGROUND

Rectourethral fistulae are complex pathologies with significant morbidity that warrant multidisciplinary care. Although gracilis muscle interposition for fistula repair has been reported, specific indications and techniques for this mode of reconstruction remain unclear.

METHODS

A retrospective quasi-experimental study was previously conducted to assess outcomes of rectourethral fistula management before and after the implementation of a multidisciplinary treatment algorithm. Patients with complex rectourethral fistulae and repair with gracilis muscle flap interposition were further investigated. Plastic surgery involvement for gracilis muscle interposition was indicated for (1) radiated rectourethral fistulae less than 3 cm and (2) nonradiated rectourethral fistulae more than 2 cm. Our preferred technique for gracilis muscle flap harvest, transposition, and inset is described in detail. Primary outcomes included healing of rectourethral fistulae and secondary reversal of urinary or fecal diversions.

RESULTS

Twenty-three patients with complex rectourethral fistulae underwent gracilis muscle flap interposition between 2001 and 2022 before (n = 12) and after (n = 11) algorithmic implementation. The frequency of definitive rectourethral fistula healing improved in the postalgorithm group by 33%. There was no significant difference in fistula healing time or the rate of urinary or fecal diversions after algorithm implementation. The technique of gracilis muscle flap interposition is also described.

CONCLUSIONS

The gracilis muscle interposition flap is a valuable reconstructive option for complex rectourethral fistula repair. Implementation of a multidisciplinary treatment algorithm including plastic surgery involvement and refinement of the operative approach was associated with improved frequency of definitive healing of rectourethral fistulae.

摘要

背景

直肠尿道瘘是一种复杂的病理状况,发病率高,需要多学科治疗。尽管已有报道采用股薄肌置入术修复瘘管,但这种重建方式的具体适应证和技术仍不明确。

方法

此前进行了一项回顾性准实验研究,以评估多学科治疗方案实施前后直肠尿道瘘的治疗效果。对患有复杂直肠尿道瘘并采用股薄肌瓣置入修复的患者进行了进一步研究。整形外科参与股薄肌置入的指征为:(1)放射性直肠尿道瘘小于3厘米;(2)非放射性直肠尿道瘘大于2厘米。详细描述了我们首选的股薄肌瓣切取、转移和植入技术。主要结局包括直肠尿道瘘愈合以及尿流改道或粪流改道的二次逆转。

结果

2001年至2022年期间,23例患有复杂直肠尿道瘘的患者在多学科治疗方案实施前(n = 12)和实施后(n = 11)接受了股薄肌瓣置入术。多学科治疗方案实施后,直肠尿道瘘最终愈合的频率提高了33%。多学科治疗方案实施后,瘘管愈合时间以及尿流改道或粪流改道的发生率没有显著差异。还描述了股薄肌瓣置入技术。

结论

股薄肌置入瓣是修复复杂直肠尿道瘘的一种有价值的重建选择。实施包括整形外科参与的多学科治疗方案并改进手术方法,与直肠尿道瘘最终愈合频率的提高相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/90a7c8098cd0/gox-13-e6662-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/85059d3f6c21/gox-13-e6662-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/300dd69692af/gox-13-e6662-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/90a7c8098cd0/gox-13-e6662-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/85059d3f6c21/gox-13-e6662-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/300dd69692af/gox-13-e6662-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b76/11964384/90a7c8098cd0/gox-13-e6662-g003.jpg

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本文引用的文献

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Outcomes of gracilis muscle interposition for rectourethral fistulas caused by treatment of prostate cancer.股薄肌间置术治疗前列腺癌治疗后直肠尿道瘘的效果。
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Gracilis muscle interposition for complex perineal fistulas: A systematic review and meta-analysis of the literature.股薄肌置入术治疗复杂性会阴瘘:文献系统评价与Meta分析
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Urology. 2022 Aug;166:257-263. doi: 10.1016/j.urology.2022.03.041. Epub 2022 May 16.
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Outcomes of an Algorithmic, Multidisciplinary Approach to Rectourethral Fistula Repair: A Pre- and Postintervention Quasi-Experimental Study.算法性多学科方法治疗直肠尿道瘘的效果:一项干预前后准实验研究。
Dis Colon Rectum. 2023 Apr 1;66(4):598-608. doi: 10.1097/DCR.0000000000002467. Epub 2022 May 4.
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Rectourethral Fistula Induced by Localised Prostate Cancer Treatment: Surgical and Functional Outcomes of Transperineal Repair with Gracilis Muscle Flap Interposition.经会阴入路带蒂股薄肌皮瓣转移修补术治疗局限性前列腺癌治疗后直肠尿道瘘:手术和功能结果。
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Gracilis Muscle Interposition for Rectourethral Fistula After Laparoscopic Prostatectomy: A Prospective Evaluation and Long-term Follow-up.腹腔镜前列腺切除术后股薄肌置入修复直肠尿道瘘:一项前瞻性评估和长期随访
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