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女性心血管健康研究优先领域的国际视角:横断面调查的定性研究结果

An International Perspective on Priority Areas for Women's Cardiovascular Health Research: Qualitative Findings From a Cross-Sectional Survey.

作者信息

Matthews Stacey, Faubert Christine, Couperthwaite Stephanie, Rowe Brian H

机构信息

Global Cardiovascular Research Funders Forum, National Heart Foundation of Australia, Melbourne, Australia.

Heart and Stroke Foundation of Canada, Toronto, Ontario, Canada.

出版信息

CJC Open. 2024 Dec 4;7(3):344-350. doi: 10.1016/j.cjco.2024.12.001. eCollection 2025 Mar.

Abstract

BACKGROUND

The Global Cardiovascular Research Funders Forum (GCRFF) unites international research funders interested in supporting cardiovascular disease (CVD) research. One focus area is women's cardiovascular health; the present study aimed to identify priority themes for future joint research funding opportunities.

METHODS

After ethics approval, a survey was developed based on literature review, GCRFF feedback, and input from methodologists/content experts. The survey comprised 3 open-ended and 5 multiple-choice questions. With the use of widespread dissemination strategies, an electronic survey portal was opened for 8 weeks, from November 15, 2023, to January 15, 2024, with various language options. Results were downloaded into a secure REDCap database for analysis. Independent theming of responses was completed by 3 reviewers until coding consensus was achieved, following which 1 coder completed the remaining theming. Descriptive statistics are reported.

RESULTS

Among the 191 responses, all 9 GCRFF countries were represented. Most respondents identified as women (74%) and clinicians/academics (77%); fewer people with lived or living experience participated (23%). Common themes included women-specific risk factors and prevention strategies (56%), life-course issues (43%), and sex- and gender-specific treatments and outcomes (36%). Common topics were CVD (66%), coronary artery disease (CAD) (18%), and heart disease (13%). Designated research pillars included clinical (52%), population health (36%), and basic science (30%). Solutions proposed included knowledge generation (71%), increased funding (55%), networking researchers (52%), and knowledge mobilisation (41%). Congruence of priority ordering was demonstrated between sex and respondent residence subgroups.

CONCLUSION

Diverse international input prioritised research in risk factors and prevention strategies specific to women and in sex- and gender-specific treatment and outcomes of heart disease, with considerations of life-course issues across all research pillars.

摘要

背景

全球心血管研究资助者论坛(GCRFF)汇聚了有志于支持心血管疾病(CVD)研究的国际研究资助者。其中一个重点领域是女性心血管健康;本研究旨在确定未来联合研究资助机会的优先主题。

方法

在获得伦理批准后,基于文献综述、GCRFF反馈以及方法学家/内容专家的意见制定了一项调查。该调查包括3个开放式问题和5个多项选择题。通过广泛的传播策略,于2023年11月15日至2024年1月15日开放了一个电子调查门户,为期8周,提供多种语言选项。结果被下载到一个安全的REDCap数据库中进行分析。由3名评审员对回复进行独立主题编码,直至达成编码共识,之后由1名编码员完成其余的主题编码。报告描述性统计结果。

结果

在191份回复中,GCRFF的所有9个国家均有代表。大多数受访者为女性(74%)和临床医生/学者(77%);有实际患病经历或正在患病的参与者较少(23%)。常见主题包括女性特有的风险因素和预防策略(56%)、生命历程问题(43%)以及性别特异性治疗和结果(36%)。常见话题有心血管疾病(66%)、冠状动脉疾病(CAD)(18%)和心脏病(13%)。指定的研究支柱包括临床(52%)、人群健康(36%)和基础科学(30%)。提出的解决方案包括知识生成(71%)、增加资金(55%)、研究人员建立网络(52%)和知识传播(41%)。性别和受访者居住亚组之间的优先排序一致性得到了证明。

结论

来自不同国家的国际意见将针对女性的风险因素和预防策略以及心脏病的性别特异性治疗和结果的研究列为优先事项,同时在所有研究支柱中都考虑了生命历程问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a3b/11963148/f91707fae9b0/gr1.jpg

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