Leoni Matteo Luigi Giuseppe, Mercieri Marco, Viswanath Omar, Cascella Marco, Rekatsina Martina, Pasqualucci Alberto, Caruso Annalisa, Varrassi Giustino
Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Department of Anesthesiology, Creighton University School of Medicine, Phoenix, AZ, USA.
Curr Pain Headache Rep. 2025 Apr 4;29(1):73. doi: 10.1007/s11916-025-01384-1.
Neuropathic pain represents a significant public health concern due to its complex pathophysiology and the disability it can cause. Despite advancements in understanding its underlying mechanisms and potential treatments, challenges persist in achieving effective management. This bibliometric analysis aims to offer a comprehensive overview of research trends, key contributors, and existing gaps in the literature on neuropathic pain, providing valuable insights to guide future studies and enhance clinical approaches.
A bibliometric analysis was conducted using the Web of Science Core Collection (WoSCC) database. Key metrics, including publication trends, citation patterns, co-authorship networks, and keyword co-occurrence, were evaluated. Statistical analyses included average annual percentage change (APC) assessments and trend forecasting with an Auto Regressive Integrated Moving Average (ARIMA) model.
A total of 9,974 studies published between 2005 and 2024 were included. Publications peaked between 2021 and 2022 but showed a slight decline thereafter, with forecasts predicting a steady increase from 2025 to 2030. Most papers were published in high-impact Q1 journals, reflecting the quality of research. Co-authorship analysis revealed central hubs of collaboration in the USA and China, with limited integration of smaller countries into the global research network. Keyword analysis identified multiple thematic clusters, including "chronic pain," "molecular mechanisms," and "clinical management." Specific gaps were noted in understanding personalized therapeutic approaches, and non-pharmacological interventions.
This analysis underscores the critical need for continued research to address gaps in diagnosis, treatment, and management of neuropathic pain. Strengthening international collaborations and fostering multidisciplinary efforts will be pivotal in advancing this field.
神经性疼痛因其复杂的病理生理学机制以及可能导致的残疾，成为一个重大的公共卫生问题。尽管在理解其潜在机制和潜在治疗方法方面取得了进展，但在实现有效管理方面仍存在挑战。这项文献计量分析旨在全面概述神经性疼痛文献的研究趋势、主要贡献者和现有差距，为指导未来研究和改进临床方法提供有价值的见解。
使用科学网核心合集（WoSCC）数据库进行文献计量分析。评估了关键指标，包括出版趋势、引用模式、共同作者网络和关键词共现情况。统计分析包括年均百分比变化（APC）评估和使用自回归积分移动平均（ARIMA）模型的趋势预测。
纳入了2005年至2024年间发表的9974项研究。出版物数量在2021年至2022年间达到峰值，但此后略有下降，预测显示从2025年到2030年将稳步增长。大多数论文发表在高影响力的Q1期刊上，反映了研究的质量。共同作者分析揭示了美国和中国的合作中心枢纽，小国融入全球研究网络的程度有限。关键词分析确定了多个主题集群，包括“慢性疼痛”“分子机制”和“临床管理”。在理解个性化治疗方法和非药物干预方面存在特定差距。
该分析强调了持续研究以解决神经性疼痛诊断、治疗和管理方面差距的迫切需求。加强国际合作和促进多学科努力对于推动该领域发展至关重要。
