Ching Patrick R, Pedersen Laura L
Division of Infectious Diseases, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, 1000 East Marshall Street, Suite 107, Richmond, VA 23298, USA; Healthcare Infection Prevention Program, Virginia Commonwealth University Health, Richmond, VA, USA.
Division of Infectious Diseases, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, 1000 East Marshall Street, Suite 107, Richmond, VA 23298, USA.
Med Clin North Am. 2025 May;109(3):705-720. doi: 10.1016/j.mcna.2024.12.011. Epub 2025 Feb 21.
Severe pneumonia is a leading cause of mortality and morbidity worldwide. Being a complex condition caused by a variety of microorganisms including bacteria, viruses, and fungi, it requires intensive care. A combination of early initiation of antimicrobial therapy and adjunctive nonantimicrobial interventions improve patient outcomes. This article reviews the most recent data on the epidemiology, microbiology, diagnosis, and management of severe pneumonia.
重症肺炎是全球死亡和发病的主要原因。作为一种由包括细菌、病毒和真菌在内的多种微生物引起的复杂病症，它需要重症监护。早期开始抗菌治疗并辅以非抗菌干预措施可改善患者预后。本文综述了重症肺炎在流行病学、微生物学、诊断和管理方面的最新数据。
