Sillanmäki Saara, Viitala Iida, Husso Annastiina
Diagnostic Imaging Center, Kuopio University Hospital, Kuopio, Finland; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Department of Cardiothoracic Surgery, Kuopio University Hospital, Kuopio, Finland.
JACC Case Rep. 2025 Apr 2;30(7):103408. doi: 10.1016/j.jaccas.2025.103408.
A coronary artery fistula (CAF) is an abnormal connection between a coronary artery and another cardiovascular lumen.
The authors report a case of a large CAF originating from the left circumflex (LCX) and draining into the lower segment of the superior vena cava, resulting a shunt ratio of 1.3. The patient also had a severe bicuspid aortic valve insufficiency and ventricular dilatation yet remained asymptomatic. A single surgical procedure was performed to address both the fistula and the valvular pathology. Postoperative computed tomography angiography revealed a reduced LCX diameter proximal to the fistula site, with evidence of smooth plaque/mild thrombosis in the LCX walls. In addition, the coronary calcium score was high. The patient was on anticoagulant and statins, with low-density lipoprotein level of 1.3 mmol/L.
A CAF between the LCX and superior vena cava is exceedingly rare, with limited cases reported and no established management guidelines, complicating clinical decision-making.
冠状动脉瘘(CAF)是冠状动脉与另一个心血管腔之间的异常连接。
作者报告一例源自左旋支(LCX)并引流至上腔静脉下段的大型CAF病例,分流比为1.3。该患者还患有严重的二叶式主动脉瓣关闭不全和心室扩张,但仍无症状。通过单一外科手术解决了瘘管和瓣膜病变问题。术后计算机断层扫描血管造影显示瘘管部位近端的左旋支直径减小,左旋支管壁有光滑斑块/轻度血栓形成的迹象。此外,冠状动脉钙化评分较高。患者正在接受抗凝治疗并服用他汀类药物,低密度脂蛋白水平为1.3 mmol/L。
左旋支与上腔静脉之间的冠状动脉瘘极为罕见,报道的病例有限且没有既定的管理指南,这使临床决策变得复杂。