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Unraveling the Mysteries of Myocardial Bridging: Left Main Anomaly Resolving With Optimal Medical Management.

作者信息

Gulin Dario, Lauermann Jörg, Qasim Raafet, Giannakoulas Christos, Barmano Neshro, Karlström Patric, Zwierzchlewski Tomasz

机构信息

Department of Cardiology, Ryhov County Hospital, Jönköping, Sweden.

Department of Cardiology, Ryhov County Hospital, Jönköping, Sweden.

出版信息

JACC Case Rep. 2025 Apr 2;30(7):103380. doi: 10.1016/j.jaccas.2025.103380.

DOI:10.1016/j.jaccas.2025.103380
PMID:40185594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12046887/
Abstract

BACKGROUND

Myocardial bridging (MB), typically a benign anomaly, poses clinical challenges when involving the left main coronary artery (LMCA), increasing the risk of myocardial ischemia.

CASE SUMMARY

A 58-year-old man presented with stable angina and worsening exertional chest pain. Diagnostic work-up, including coronary angiography, intravascular ultrasound, and computed tomography angiography, confirmed LMCA MB with significant flow obstruction. A tailored pharmacologic regimen involving beta-blockers and calcium antagonists led to complete symptom resolution over 6 months.

DISCUSSION

Although MB often lacks symptoms, cases affecting the LMCA require careful assessment due to potential ischemic complications in broader territories. This case highlights the importance of comprehensive imaging and functional evaluation in managing MB and supports pharmacologic management over invasive procedures when feasible, aligning with recent literature advocating conservative treatment outcomes.

TAKE-HOME MESSAGE: Accurate diagnosis and personalized medical management are crucial in MB cases even if involving critical coronary arteries such as the LMCA.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/d1ee4cb3cc2f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/9ceeb1039717/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/c4f093eb7958/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/8b3da624f4ce/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/c3c37ebe282d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/d1ee4cb3cc2f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/9ceeb1039717/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/c4f093eb7958/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/8b3da624f4ce/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/c3c37ebe282d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2737/12046887/d1ee4cb3cc2f/gr4.jpg

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本文引用的文献

1
A Comprehensive Review of Myocardial Bridging: Exploring Diagnostic and Treatment Modalities.心肌桥的全面综述:探索诊断与治疗方式
Cureus. 2023 Aug 8;15(8):e43132. doi: 10.7759/cureus.43132. eCollection 2023 Aug.
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Myocardial Bridging: Diagnosis, Functional Assessment, and Management: JACC State-of-the-Art Review.心肌桥:诊断、功能评估与管理:美国心脏病学会最新临床综述。
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Myocardial bridges: A meta-analysis.心肌桥:荟萃分析。
Clin Anat. 2021 Jul;34(5):685-709. doi: 10.1002/ca.23697. Epub 2021 Feb 22.
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Myocardial bridging.心肌桥
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Update on myocardial bridging.心肌桥的最新进展。
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