环境因素对呼吸道微生物群和呼吸系统疾病的影响。
The impact of environmental factors on respiratory tract microbiome and respiratory system diseases.
作者信息
Ge Yutao, Tang Guo, Fu Yawen, Deng Peng, Yao Rong
机构信息
Emergency Department of West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu, 610041, Sichuan, China.
出版信息
Eur J Med Res. 2025 Apr 4;30(1):236. doi: 10.1186/s40001-025-02517-3.
The respiratory tract microbiome, a complex ecosystem of microorganisms colonizing the respiratory mucous layers and epithelial surfaces along with their associated microenvironment, plays a vital role in maintaining respiratory function and promoting the maturation of the respiratory immune system. Current research suggests that environmental changes can disrupt the respiratory microbiota, potentially leading to disease. This review summarizes existing research on the impact of environmental factors on the respiratory microbiome and associated diseases, aiming to offer new insights into the prevention and treatment of respiratory disease.
呼吸道微生物群是一个复杂的微生物生态系统，这些微生物连同其相关的微环境一起定殖在呼吸道粘膜层和上皮表面，在维持呼吸功能和促进呼吸道免疫系统成熟方面发挥着至关重要的作用。目前的研究表明，环境变化会破坏呼吸道微生物群，可能导致疾病。这篇综述总结了关于环境因素对呼吸道微生物群及相关疾病影响的现有研究，旨在为呼吸道疾病的预防和治疗提供新的见解。
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