Altıner Saygın, Aydoğdu Yunushan Furkan, Kosmaz Koray, Durhan Abdullah, Senlikci Abdullah, Suleyman Marlen, Ersak Can, Pekcici Mevlüt Recep
General Surgery Department , Gazi University Faculty of Medicine, Ankara, Turkey.
Department of General Surgery, Ankara Training And Research Hospital, Ankara, Turkey.
Int J Colorectal Dis. 2025 Apr 5;40(1):88. doi: 10.1007/s00384-025-04866-1.
This study aimed to investigate the relationship between colonic diverticulosis, colorectal polyps, and colorectal cancer.
A total of 648 patients (275 females, 373 males) who underwent complete colonoscopy between January 2016 and June 2020 were retrospectively analyzed. The presence and localization of diverticula, polyps, and cancer were recorded, and the association between diverticular disease and the formation of polyps and cancer was evaluated.
Diverticula were identified in 53 patients (8.2%), while 595 patients (91.8%) had no diverticula. Polyps were detected in 148 patients (22.8%), and no polyps were found in 500 patients (77.2%). Adenocarcinoma was diagnosed in 67 patients (10.3%), with no malignancy observed in 581 patients (89.7%). The mean age of patients with polyps was 59.5 years, compared to 53.3 years in those without polyps (p < 0.001). Multivariate logistic regression analysis revealed that diverticulum status did not significantly influence the risk of polyp formation, whereas advanced age was identified as a significant risk factor (p < 0.001).
Advanced age is a significant risk factor for colorectal polyp formation, whereas diverticulosis is not an independent risk factor. These findings highlight the importance of age-based screening strategies for colorectal neoplasia.
本研究旨在调查结肠憩室病、结直肠息肉与结直肠癌之间的关系。
回顾性分析了2016年1月至2020年6月期间接受全结肠镜检查的648例患者（275例女性，373例男性）。记录憩室、息肉和癌症的存在情况及定位，并评估憩室病与息肉和癌症形成之间的关联。
53例患者（8.2%）发现有憩室，595例患者（91.8%）无憩室。148例患者（22.8%）检测到息肉，500例患者（77.2%）未发现息肉。67例患者（10.3%）被诊断为腺癌，581例患者（89.7%）未观察到恶性肿瘤。有息肉患者的平均年龄为59.5岁，无息肉患者为53.3岁（p<0.001）。多因素逻辑回归分析显示，憩室状态对息肉形成风险无显著影响，而高龄被确定为显著风险因素（p<0.001）。
高龄是结直肠息肉形成的显著风险因素，而憩室病不是独立的风险因素。这些发现凸显了基于年龄的结直肠肿瘤筛查策略的重要性。
