Bhuvaneswaran Kartha Gayathri, Irene Varghese Shruti, Krupa Jesu, George Alex Anoop, George Oommen K, Samuel Thomson Viji
Department of Cardiology, Christian Medical College, Vellore, India.
Department of Cardiology, Christian Medical College, Vellore, India.
Indian Heart J. 2025 May-Jun;77(3):231-234. doi: 10.1016/j.ihj.2025.04.001. Epub 2025 Apr 4.
A hemodynamically significant patent ductus arteriosus (PDA) may be associated with mitral regurgitation (MR). Available treatment strategies are - surgical PDA ligation ± mitral valve surgery and initial transcatheter PDA closure (PDA-DC) with treatment of MR subsequently, if necessary. We aimed to describe the fate of MR after PDA-DC in patients with PDA and significant MR. On retrospective review of electronic health records between 2013 and 2023, 14 eligible patients were identified. Amongst them, PDA-DC resulted in symptomatic improvement in all. A reduction in the severity of MR was noted in 12 patients (85.7 %).
具有血流动力学意义的动脉导管未闭(PDA)可能与二尖瓣反流(MR)有关。现有的治疗策略包括——外科手术结扎PDA ± 二尖瓣手术,以及必要时先进行经导管封堵PDA(PDA-DC),随后再治疗MR。我们旨在描述PDA合并严重MR患者在进行PDA-DC后MR的转归情况。通过回顾性分析2013年至2023年的电子健康记录,确定了14例符合条件的患者。其中,所有患者经PDA-DC后症状均有改善。12例患者(85.7%)的MR严重程度有所降低。