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动脉导管未闭经导管封堵术后二尖瓣反流的转归:单中心研究

Fate of mitral regurgitation after transcatheter closure of patent ductus arteriosus: single centre study.

作者信息

Bhuvaneswaran Kartha Gayathri, Irene Varghese Shruti, Krupa Jesu, George Alex Anoop, George Oommen K, Samuel Thomson Viji

机构信息

Department of Cardiology, Christian Medical College, Vellore, India.

Department of Cardiology, Christian Medical College, Vellore, India.

出版信息

Indian Heart J. 2025 May-Jun;77(3):231-234. doi: 10.1016/j.ihj.2025.04.001. Epub 2025 Apr 4.

DOI:10.1016/j.ihj.2025.04.001
PMID:40189097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12223595/
Abstract

A hemodynamically significant patent ductus arteriosus (PDA) may be associated with mitral regurgitation (MR). Available treatment strategies are - surgical PDA ligation ± mitral valve surgery and initial transcatheter PDA closure (PDA-DC) with treatment of MR subsequently, if necessary. We aimed to describe the fate of MR after PDA-DC in patients with PDA and significant MR. On retrospective review of electronic health records between 2013 and 2023, 14 eligible patients were identified. Amongst them, PDA-DC resulted in symptomatic improvement in all. A reduction in the severity of MR was noted in 12 patients (85.7 %).

摘要

具有血流动力学意义的动脉导管未闭(PDA)可能与二尖瓣反流(MR)有关。现有的治疗策略包括——外科手术结扎PDA ± 二尖瓣手术,以及必要时先进行经导管封堵PDA(PDA-DC),随后再治疗MR。我们旨在描述PDA合并严重MR患者在进行PDA-DC后MR的转归情况。通过回顾性分析2013年至2023年的电子健康记录,确定了14例符合条件的患者。其中,所有患者经PDA-DC后症状均有改善。12例患者(85.7%)的MR严重程度有所降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97e0/12223595/a9969dda2180/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97e0/12223595/a9969dda2180/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97e0/12223595/a9969dda2180/gr1.jpg

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本文引用的文献

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JACC Adv. 2024 Aug 24;3(10):101211. doi: 10.1016/j.jacadv.2024.101211. eCollection 2024 Oct.
2
Transcatheter and Surgical Ductus Arteriosus Closure in Very Low Birth Weight Infants: 2018-2022.经导管和手术动脉导管未闭封堵术在极低出生体重儿中的应用:2018-2022 年。
Pediatrics. 2024 Aug 1;154(2). doi: 10.1542/peds.2024-065905.
3
Infant Mitral Valve Replacement: Current State of the Art.婴儿二尖瓣置换术:现状。
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2023;26:75-80. doi: 10.1053/j.pcsu.2023.01.001. Epub 2023 Jan 16.
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Trend and Outcomes for Surgical Versus Transcatheter Patent Ductus Arteriosus Closure in Neonates and Infants at US Children's Hospitals.美国儿童医院新生儿和婴儿经导管与经手术动脉导管未闭封堵术的趋势和结局。
J Am Heart Assoc. 2022 Jan 4;11(1):e022776. doi: 10.1161/JAHA.121.022776. Epub 2021 Dec 31.
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Correction to: 2020 ACC/AHA Guideline on the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Circulation. 2021 Feb 2;143(5):e229. doi: 10.1161/CIR.0000000000000955. Epub 2021 Feb 1.
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Comparison of transcatheter patent ductus arteriosus closure between children and adults.儿童与成人经导管动脉导管未闭封堵术的比较。
Heart Vessels. 2020 Nov;35(11):1605-1613. doi: 10.1007/s00380-020-01639-4. Epub 2020 Jun 3.
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Commentary: Mitral Valve Repair in the Very Young: A Story of Risk and Reward.
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