心律失常性二尖瓣脱垂：病理生理学、诊断及管理策略
Arrhythmic Mitral Valve Prolapse: Pathophysiology, Diagnostics, and Management Strategies.
作者信息
Kang Jagdip, van Kampen Antonia, Dieterlen Maja-Theresa, Spampinato Ricardo, Sundt Thoralf, Melnitchouk Serguei, Levine Robert A, Borger Michael A
机构信息
University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany; Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany.
出版信息
Semin Thorac Cardiovasc Surg. 2025 Apr 4. doi: 10.1053/j.semtcvs.2025.03.005.
Abstract
Mitral valve prolapse (MVP) is a common disease in which ventricular arrhythmias/sudden cardiac death can be the first symptom of presentation. This review article explores the current understanding of underlying pathological mechanisms leading to an increased risk for ventricular arrhythmias in the setting of MVP and elaborates on the current evidence regarding the diagnosis and management of the disease.
摘要
二尖瓣脱垂（MVP）是一种常见疾病，室性心律失常/心源性猝死可能是其首发症状。这篇综述文章探讨了目前对导致MVP患者室性心律失常风险增加的潜在病理机制的理解，并阐述了有关该疾病诊断和管理的现有证据。
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本文引用的文献
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Arrhythmogenic Mitral Valve Prolapse: Can We Risk Stratify and Prevent Sudden Cardiac Death?致心律失常性二尖瓣脱垂：我们能否进行风险分层并预防心源性猝死？
Arrhythm Electrophysiol Rev. 2024 Jul 23;13:e11. doi: 10.15420/aer.2023.26. eCollection 2024.
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Noncomplex ventricular arrhythmia associated with greater freedom from recurrent ectopy at 1 year after mitral repair surgery.二尖瓣修复手术后1年，非复杂性室性心律失常与更低的反复异位发生率相关。
JTCVS Open. 2024 Apr 18;19:94-113. doi: 10.1016/j.xjon.2024.04.005. eCollection 2024 Jun.
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Degenerative mitral regurgitation.退行性二尖瓣反流
Nat Rev Dis Primers. 2023 Dec 7;9(1):70. doi: 10.1038/s41572-023-00478-7.
4
Left ventricular fibrosis and CMR tissue characterization of papillary muscles in mitral valve prolapse patients.二尖瓣脱垂患者左心室纤维化和心脏磁共振组织特征。
Int J Cardiovasc Imaging. 2024 Feb;40(2):213-224. doi: 10.1007/s10554-023-02985-w. Epub 2023 Oct 28.
5
Arrhythmic Mitral Valve Prolapse With Only Mild or Moderate Mitral Regurgitation: Characterization of Myocardial Substrate.心律失常性二尖瓣脱垂伴仅有轻度或中度二尖瓣反流：心肌基质特征。
JACC Clin Electrophysiol. 2023 Aug;9(8 Pt 3):1709-1716. doi: 10.1016/j.jacep.2023.04.011. Epub 2023 May 24.
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The impact of mitral valve surgery on ventricular arrhythmias in patients with Barlow's disease: preliminary results of a prospective study.二尖瓣手术对巴洛氏病患者室性心律失常的影响：一项前瞻性研究的初步结果。
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