Said Fares Kassandra, Hani Abi Tayeh Georges, Roger Whaibeh Emile, Jihad Louis Romy, Yasser Jaalouk Lina, Matar Matar Yara, Andraos Mrad Myriam
Higher Institute for Public Health, Saint Joseph University of Beirut, Beirut, Lebanon.
Saint Joseph Fertility Center, Beirut, Lebanon.
Int J Reprod Biomed. 2025 Mar 21;23(1):1-16. doi: 10.18502/ijrm.v23i1.18188. eCollection 2025 Jan.
According to the World Health Organization, 17.5% of the population suffers from infertility. This demonstrates the critical need to expand access to high-quality reproductive care and increase our understanding of the factors that contribute to this issue. This review aims to summarize findings and gaps in the literature regarding diet-related factors and infertility among the Eastern Mediterranean couples poorly studied compared to other populations. The literature search was conducted using PubMed and Scopus databases from January 2012-July 2023. In total, 112 papers described the influence of diet and supplementation on natural and artificial reproductive outcomes in the Eastern Mediterranean Region and were found eligible for the review synthesis. For men, a diet rich in red meat, fatty foods, whole grains, and low in fish, poultry, low-fat dairy products, and vegetables have a positive effect on sperm count. For women, maintaining a healthy weight is crucial for their fertility. Overall, various vitamins and supplements significantly enhance gametes quality, hormonal balance, and antioxidant capacity, despite the results not being consistent across all studies. The findings highlight distinct dietary patterns that mitigate or exacerbate infertility risks, considering macro and micronutrients. Studies unevenly describe potential risk factors, underscoring the need for further exploration across diverse populations.
根据世界卫生组织的数据，17.5%的人口患有不孕症。这表明迫切需要扩大获得高质量生殖保健的机会，并加深我们对导致这一问题的因素的理解。本综述旨在总结与饮食相关因素以及东地中海地区夫妇不孕症相关的文献研究结果和空白，与其他人群相比，该地区的研究较少。文献检索使用了2012年1月至2023年7月的PubMed和Scopus数据库。总共发现112篇论文描述了饮食和补充剂对东地中海地区自然和人工生殖结果的影响，这些论文符合综述综合的条件。对男性而言，富含红肉、高脂肪食物、全谷物且鱼类、家禽、低脂乳制品和蔬菜摄入量低的饮食对精子数量有积极影响。对女性而言，保持健康体重对其生育能力至关重要。总体而言，尽管并非所有研究结果都一致，但各种维生素和补充剂能显著提高配子质量、激素平衡和抗氧化能力。研究结果突出了不同的饮食模式，这些模式考虑了宏量营养素和微量营养素，会减轻或加剧不孕风险。研究对潜在风险因素的描述不均衡，强调需要在不同人群中进一步探索。
