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黏液样软骨肉瘤的节段性切除:一例报告

Segmental resection of myxoid chondrosarcoma: a case report.

作者信息

Liu Qinghao, Wu Xing, Zhao Weiwen, Peng Junjie, Yin Hao

机构信息

The Department of Orthopedics, The First Affiliated Hospital of Hunan Normal University Hunan Provincial People's Hospital, Changsha, China.

The Department of Orthopedics, Changsha Hospital of Traditional Chinese Medicine, Changsha, China.

出版信息

Front Oncol. 2025 Mar 21;15:1525039. doi: 10.3389/fonc.2025.1525039. eCollection 2025.

DOI:10.3389/fonc.2025.1525039
PMID:40190554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11969337/
Abstract

We report a rare case of extradural spinal chondrosarcoma in a 48-year-old female. The patient was asymptomatic until a traumatic injury led to lumbar pain, revealing a tumor with atypical imaging characteristics in adjacent vertebral segments. MRI confirmed an extradural spinal tumor, which was surgically excised. Histopathological examination identified the tumor as myxoid chondrosarcoma. The patient underwent extensive surgical treatment, with no local recurrence or distant metastasis observed after five years. Her lumbar pain also completely resolved within the first postoperative year. The management of the rare entity of spinal canal chondrosarcoma is discussed.

摘要

我们报告了一例48岁女性的硬膜外脊髓软骨肉瘤罕见病例。该患者在遭受外伤导致腰痛之前没有症状,外伤后发现相邻椎体节段有具有非典型影像学特征的肿瘤。MRI证实为硬膜外脊髓肿瘤,遂进行手术切除。组织病理学检查确定该肿瘤为黏液样软骨肉瘤。患者接受了广泛的手术治疗,五年后未观察到局部复发或远处转移。她的腰痛在术后第一年内也完全缓解。本文讨论了椎管软骨肉瘤这一罕见实体的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/0dae9601286b/fonc-15-1525039-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/01944e08abf0/fonc-15-1525039-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/3087d343e675/fonc-15-1525039-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/10d32d4d5322/fonc-15-1525039-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/0dae9601286b/fonc-15-1525039-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/01944e08abf0/fonc-15-1525039-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/3087d343e675/fonc-15-1525039-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/10d32d4d5322/fonc-15-1525039-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d00/11969337/0dae9601286b/fonc-15-1525039-g004.jpg

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本文引用的文献

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A total en bloc spondylectomy and reconstruction of vertebra thoracal IV-VI in primary large chondrosarcoma: A rare surgical case report.原发性巨大软骨肉瘤全椎体整块切除术及胸4-6椎体重建:1例罕见手术病例报告
Int J Surg Case Rep. 2024 Nov;124:110391. doi: 10.1016/j.ijscr.2024.110391. Epub 2024 Sep 30.
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Collection of Rare Peripheral Nerve Tumors-Insights from the German Registry.罕见周围神经肿瘤的收集——来自德国登记处的见解
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Clinical Features and Surgical Management of Intramedullary Schwannoma of the Spinal Cord.
脊髓髓内神经鞘瘤的临床特征和外科治疗。
World Neurosurg. 2024 May;185:e1280-e1286. doi: 10.1016/j.wneu.2024.03.070. Epub 2024 Mar 19.
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Skull-Base Chondrosarcoma: A Systematic Review of the Role of Postoperative Radiotherapy.颅底软骨肉瘤:术后放疗作用的系统评价
Cancers (Basel). 2024 Feb 21;16(5):856. doi: 10.3390/cancers16050856.
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A Systematic Review of Adjuvant Chemotherapy in Localized Dedifferentiated Chondrosarcoma.局限性去分化软骨肉瘤辅助化疗的系统评价
Curr Oncol. 2024 Jan 19;31(1):566-578. doi: 10.3390/curroncol31010040.
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Primary Osseous Malignancies of the Spine.脊柱原发性骨恶性肿瘤
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Chondrosarcoma: A Clinical Review.软骨肉瘤:临床综述
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Curr Treat Options Oncol. 2022 Feb;23(2):199-209. doi: 10.1007/s11864-022-00951-7. Epub 2022 Feb 21.
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