Xu Zhe, Wang Jingwen, Shi Ce, Ni Shuang, Xu Jingwei, Zhu Sha, Fang Jianxia, Xu Wen
Eye Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Zhejiang Provincial Key Laboratory of Ophthalmology, Hangzhou, Zhejiang, China.
Sci Rep. 2025 Apr 7;15(1):11881. doi: 10.1038/s41598-025-97040-0.
The prospective study is aimed to determine the clinical outcomes of plate-haptic diffractive multifocal toric intraocular lens (IOL) implantation in cataract patients with long axial length and corneal astigmatism. Visual outcomes, defocus curves, contrast sensitivity, rotational stability, vector changes of refractive astigmatism and patient satisfaction were assessed over 3 months. Vector analysis was performed by the Alpins method. A total of 36 eyes (18 patients) underwent cataract surgery with implantation of AT LISA toric 909 M multifocal toric IOL. Preoperatively, mean axial length AL was 27.31 ± 2.20 mm. Mean manifest sphere and cylinder were - 6.66 ± 5.37 diopter (D) and - 1.88 ± 1.11 D. Postoperatively, mean manifest sphere and cylinder were reduced to 0.13 ± 0.23 D and - 0.29 ± 0.32 D, respectively (P < 0.05, Wilcoxon test). Mean uncorrected distance and near visual acuities (logMAR) were 0.40 ± 0.10 and 0.19 ± 0.16, respectively. At 3 months, 91.7% of patients showed IOL rotation of less than 5 degrees. The difference vector was 0.34 ± 0.26 D, for a correction index of 0.93 ± 0.40 at 3 months. In summary, plate-haptic diffractive multifocal toric IOL improves distance and near visual functions and reduces refractive astigmatism in cataract patients with long axial length and corneal astigmatism.Trial registration: NCT04833491.
这项前瞻性研究旨在确定在眼轴长度较长且有角膜散光的白内障患者中植入板式触觉衍射多焦点环曲面人工晶状体(IOL)的临床结果。在3个月的时间里评估了视觉结果、散焦曲线、对比敏感度、旋转稳定性、屈光性散光的矢量变化和患者满意度。采用阿尔平斯方法进行矢量分析。共有36只眼(18例患者)接受了白内障手术并植入了AT LISA toric 909 M多焦点环曲面IOL。术前,平均眼轴长度(AL)为27.31±2.20毫米。平均显性球镜和柱镜分别为-6.66±5.37屈光度(D)和-1.88±1.11 D。术后,平均显性球镜和柱镜分别降至0.13±0.23 D和-0.29±0.32 D(P<0.05,Wilcoxon检验)。平均未矫正远视力和近视力(logMAR)分别为0.40±0.10和0.19±0.16。在3个月时,91.7%的患者人工晶状体旋转小于5度。差异矢量为0.34±0.26 D,3个月时矫正指数为0.93±0.40。总之,板式触觉衍射多焦点环曲面IOL改善了眼轴长度较长且有角膜散光的白内障患者的远视力和近视力功能,并减少了屈光性散光。试验注册号:NCT04833491。