Ma Dongmei, Han Xiaoyan, Hua Zhixiang, Shen Jiying, Zhang Limei, Qiu Tian, Luo Jianfeng, Cai Lei, Yang Jin
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Rd., Xuhui District, Shanghai, China.
NHC Key Laboratory of Myopia, Fudan University; Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.
Graefes Arch Clin Exp Ophthalmol. 2023 Apr;261(4):989-998. doi: 10.1007/s00417-022-05851-y. Epub 2022 Oct 6.
To assess the contribution of capsular tension ring (CTR) to postoperative stability and visual outcomes of a plate-haptic toric intraocular lens (IOL).
This prospective cohort study was performed among patients underwent toric IOL (AT TORBI 709 M) implantation with or without CTR at the Eye and ENT hospital between April 2020 and November 2021. Propensity score matching (PSM) was performed to balance baseline factors. Postoperatively, uncorrected distance visual acuity (UCVA) and residual astigmatism, as well as IOLs' rotation, tilt, and decentration, were analyzed. Grouped multiple linear regression analysis was used to model predictive factors of rotation in each group. Additionally, a meta-analysis of data from 4 publications (284 eyes) and current study was performed to evaluate the effect of CTR co-implantation on toric IOL rotation.
After PSM, 126 eyes from each group were included for further analysis. Postoperatively, UDVA was 0.31 ± 0.38 logMAR and 0.27 ± 0.36 logMAR in the CTR and NCTR groups, respectively (P = 0.441), and residual astigmatism was 0.75 ± 0.52 D and 0.86 ± 0.65 D, respectively (P = 0.139). The rotation of toric IOL was significantly smaller in the CTR group than in the NCTR group (4.63 ± 6.27 vs. 10.93 ± 16.05 degrees, P < 0.001). The regression models of the two groups and the coefficients of LT were significantly different (P < 0.001 and P = 0.001, respectively). Furthermore, the meta-analysis confirmed that CTR co-implantation reduced toric IOL rotation (MD, - 1.59; 95% CI, - 3.10 to - 0.09; P = 0.038).
CTR enhances rotational stability of toric IOL by reducing the impact of LT, and CTR co-implantation is recommended in patients with lens thickness (LT) ≥ 4.5 mm, white-to-white (WTW) ≥ 11.6 mm, or high preexisting astigmatism.
评估囊袋张力环(CTR)对带襻平板型散光人工晶状体(IOL)术后稳定性和视觉效果的作用。
本前瞻性队列研究于2020年4月至2021年11月期间在眼耳鼻喉医院对接受或未接受CTR植入的散光IOL(AT TORBI 709 M)植入患者进行。采用倾向评分匹配(PSM)来平衡基线因素。术后,分析未矫正远视力(UCVA)、残余散光以及IOL的旋转、倾斜和偏心情况。采用分组多元线性回归分析对每组中旋转的预测因素进行建模。此外,对4篇文献(284只眼)的数据和本研究进行荟萃分析,以评估CTR联合植入对散光IOL旋转的影响。
PSM后,每组纳入126只眼进行进一步分析。术后,CTR组和无CTR组的UDVA分别为0.31±0.38 logMAR和0.27±0.36 logMAR(P = 0.441),残余散光分别为0.75±0.52 D和0.86±0.65 D(P = 0.139)。CTR组散光IOL的旋转明显小于无CTR组(4.63±6.27对10.93±16.05度,P < 0.001)。两组的回归模型和晶状体厚度(LT)系数有显著差异(分别为P < 0.001和P = 0.001)。此外,荟萃分析证实CTR联合植入可减少散光IOL的旋转(MD, -1.59;95% CI, -3.10至 -0.09;P = 0.038)。
CTR通过减少LT的影响增强了散光IOL的旋转稳定性,对于晶状体厚度(LT)≥4.5 mm、白对白(WTW)≥11.6 mm或术前散光较高的患者,建议联合植入CTR。