Rishi Kirti, Ibrahim Mohamed A
Anesthesiology, University of Texas Medical Branch, Galveston, USA.
Cureus. 2025 Mar 7;17(3):e80207. doi: 10.7759/cureus.80207. eCollection 2025 Mar.
Congenital third-degree complete heart block (CHB) detected during pregnancy is a rare condition. This report discusses a pregnant patient with an incidental finding of CHB and its implications for maternal and fetal outcomes. A 21-year-old female patient, gravida 2 para 0 (G2P0010), first registered at five weeks, two days gestation, with an incidental finding of third-degree heart block. Her baseline heart rate of 40-50 beats per minute, with no prior cardiac diagnosis. She had a history of miscarriage at six weeks' gestation. During the current pregnancy, she experienced two episodes of dizziness upon standing, each resolving within a minute without signs of hemodynamic instability. A 12-lead EKG and 24-hour Holter monitoring confirmed CHB, and echocardiography ruled out secondary causes. Cardiology and electrophysiology recommended temporary transcutaneous pacing and bedside atropine in case of instability. CHB in pregnancy is often congenital and characterized by independent ventricular activity due to atrial stimulus blockage. While typically asymptomatic, symptoms such as dizziness, hypotension, syncope, severe bradycardia, and cardiac arrest can occur. Pregnancy and labor stress, including the Valsalva maneuver, can exacerbate bradyarrhythmia, leading to adverse outcomes. Inadequate fetal perfusion and oxygenation can result in fetal bradycardia and hypoxia. Management requires a multidisciplinary approach, with echocardiograms, Holter monitoring, and, in some cases, cardiac MRI to rule out structural heart disease. Asymptomatic patients with good functional capacity may avoid permanent pacemakers, though temporary pacing is considered on a case-by-case basis. Neuraxial anesthesia is preferred for cesarean delivery in both symptomatic and asymptomatic CHB patients due to its minimal impact on myocardial function. General anesthesia should be avoided when possible. If necessary, anesthetic agents with minimal cardiac depression, such as ketamine, etomidate, rocuronium, and isoflurane, are recommended. Assisted early deliveries, such as vacuum or forceps, can help reduce the risk of Valsalva-induced bradycardia. Asymptomatic CHB cases without significant heart disease typically have favorable outcomes. However, careful cardiovascular monitoring and individualized care plans are essential to mitigate potential complications. Postpartum cardiology follow-up is necessary to assess the development of new symptoms and determine the need for a permanent pacemaker. This case highlights the importance of early diagnosis, adequate monitoring, early elective delivery, and multidisciplinary management in CHB during pregnancy. Neuraxial anesthesia and strategic labor management are key to ensuring positive maternal and fetal outcomes. Further research is needed to develop standardized guidelines for this rare condition.
孕期检测出先天性三度完全性心脏传导阻滞(CHB)是一种罕见的情况。本报告讨论了一名意外发现患有CHB的孕妇及其对母婴结局的影响。一名21岁女性患者,孕2产0(G2P0010),妊娠5周零2天时首次登记,意外发现三度心脏传导阻滞。她的基础心率为每分钟40 - 50次,既往无心脏诊断史。她有过一次妊娠6周时流产的病史。在本次妊娠期间,她站立时出现过两次头晕,每次均在1分钟内缓解,无血流动力学不稳定迹象。12导联心电图和24小时动态心电图监测确诊为CHB,超声心动图排除了继发性病因。心脏病学和电生理学建议在出现不稳定情况时进行临时经皮起搏和床边使用阿托品。孕期CHB通常是先天性的,其特征是由于心房刺激受阻导致心室独立活动。虽然通常无症状,但可能会出现头晕、低血压、晕厥、严重心动过缓和心脏骤停等症状。妊娠和分娩应激,包括瓦尔萨尔瓦动作,可加重缓慢性心律失常,导致不良后果。胎儿灌注和氧合不足可导致胎儿心动过缓和缺氧。管理需要多学科方法,包括超声心动图、动态心电图监测,在某些情况下还需要心脏磁共振成像以排除结构性心脏病。功能能力良好的无症状患者可能无需永久起搏器,不过需根据具体情况考虑临时起搏。对于有症状和无症状的CHB患者,剖宫产时首选神经轴麻醉,因为其对心肌功能影响最小。尽可能避免全身麻醉。如有必要,建议使用对心脏抑制作用最小的麻醉剂,如氯胺酮、依托咪酯、罗库溴铵和异氟烷。辅助早期分娩,如真空吸引或产钳助产,有助于降低瓦尔萨尔瓦动作诱发心动过缓的风险。无明显心脏病的无症状CHB病例通常预后良好。然而,仔细的心血管监测和个性化护理计划对于减轻潜在并发症至关重要。产后心脏病学随访对于评估新症状的出现以及确定是否需要永久起搏器是必要的。本病例强调了孕期CHB早期诊断、充分监测、早期择期分娩和多学科管理的重要性。神经轴麻醉和策略性分娩管理是确保母婴良好结局的关键。需要进一步研究以制定针对这种罕见情况的标准化指南。