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结节病的假瘤表型

Pseudotumor Phenotype of Sarcoidosis.

作者信息

Lakhal Mohamed, Rhazari Meriem, Gartini Sara, Meziane Mohammed, Thouil Afaf, Bennani Amal, Kouismi Hatim

机构信息

Department of Respiratory Diseases, Mohamed VI University Hospital Center of Oujda, Faculty of Medicine and Pharmacy of Oujda, Oujda, MAR.

Department of Pulmonology, Research and Medical Sciences Laboratory, Mohamed VI University Hospital Center of Oujda, Faculty of Medicine and Pharmacy of Oujda, Oujda, MAR.

出版信息

Cureus. 2025 Mar 8;17(3):e80245. doi: 10.7759/cureus.80245. eCollection 2025 Mar.

Abstract

Sarcoidosis is a benign multi-system granulomatous disease of unknown etiology. It can occasionally present with a pseudo-tumoral appearance, constituting a diagnostic pitfall that should be considered. We report the case of an 84-year-old patient with no significant medical history, admitted for the management of chronic dyspnea associated with chest pain evolving over the past six months, in the context of a preserved general condition. A chest CT scan revealed a pulmonary process, and the histopathological examination confirmed sarcoidosis. Through this case, we highlight the unique presentation of pulmonary sarcoidosis with a pseudo-tumoral pattern, which is often challenging to diagnose. The discrepancy between the subtle clinical presentation and the extent of radiological lesions should, however, raise suspicion of this diagnosis. Histological confirmation is necessary to rule out other potential etiologies, particularly tumors.

摘要

结节病是一种病因不明的良性多系统肉芽肿性疾病。它偶尔可呈现假瘤样外观,这构成了一个应予以考虑的诊断陷阱。我们报告一例84岁患者,既往无重大病史,因过去六个月出现的与胸痛相关的慢性呼吸困难入院治疗,总体状况良好。胸部CT扫描显示肺部病变,组织病理学检查确诊为结节病。通过这个病例,我们强调了肺部结节病具有假瘤样表现的独特呈现方式,这种情况通常诊断具有挑战性。然而,轻微的临床表现与放射学病变范围之间的差异应引起对该诊断的怀疑。组织学确诊对于排除其他潜在病因,尤其是肿瘤,是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f7/11974230/a47baa9317c2/cureus-0017-00000080245-i02.jpg

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