Janani Sree C M, Rangarajan Sudha, Preethi P Sai, S Adikrishnan
Dermatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus. 2025 Mar 8;17(3):e80247. doi: 10.7759/cureus.80247. eCollection 2025 Mar.
Background and objective Menopause is a significant phase that marks the end of the reproductive years in women and heralds various physiological, hormonal, and psychological changes. There is scarce research on dermatoses in menopause, particularly in developing countries, where many cases go unreported or undiagnosed due to limited healthcare access and awareness. The study aimed to analyze the clinical pattern of dermatoses in postmenopausal women. Methods We conducted a cross-sectional study involving 200 cases of postmenopausal women with dermatoses in any area of the body treated at the Dermatology OPD, Sri Ramachandra Institute of Higher Education and Research (SRIHER) for a period of two years (July 2022-July 2024). A semi-structured questionnaire was circulated, which sought to document data on age, presenting complaints, associated symptoms suggestive of any underlying autoimmune, connective tissue disorder or malignancy, personal and family H/O diabetes mellitus, hypertension, endocrine disorders, cardiovascular diseases, dietary and menstrual history, socioeconomic history, sanitation history, and obstetric history. Results The study included a total of 200 postmenopausal patients who were evaluated for cutaneous, hair, nail, and oral cavity changes. The mean age of the participants was 58.99 ±9.12 years. The age at which menopause started was 40-50 years for most participants (n=127, 63.5%). Occupation-wise, most participants were housewives (n=178, 85.5%). Wrinkles, observed in 149 patients (74.5%), were the common physiological change noted. Of the pathological changes, fungal infections like tinea (n=29, 14.5%) were the most common. Among eczematous conditions, asteatotic eczema, observed in nine patients (4.5%), was the most common; as for papulosquamous disorders, psoriasis (n=22, 11%) was the most frequent condition. Seborrheic keratosis (n=43, 21.5%) was the most frequent benign tumor; regarding psychocutaneous disorders, lichen simplex chronicus (n=3, 1.5%) was the most commonly encountered condition. Conclusions Postmenopausal dermatoses represent a significant but underrecognized issue related to women's health in India. This study highlights the prevalence of conditions like atrophic vaginitis, lichen planus, and fungal infections in our postmenopausal population.
背景与目的 更年期是女性生殖期结束的一个重要阶段,预示着各种生理、激素和心理变化。关于更年期皮肤病的研究很少,尤其是在发展中国家,由于医疗服务可及性和认知度有限,许多病例未被报告或诊断。本研究旨在分析绝经后女性皮肤病的临床模式。方法 我们进行了一项横断面研究,纳入了在斯里兰卡拉马钱德拉高等教育与研究学院(SRIHER)皮肤科门诊接受治疗的200例身体任何部位患有皮肤病的绝经后女性,为期两年(2022年7月至2024年7月)。发放了一份半结构化问卷,旨在记录年龄、主诉、提示任何潜在自身免疫性、结缔组织疾病或恶性肿瘤的相关症状、个人及家族糖尿病、高血压、内分泌疾病、心血管疾病病史、饮食和月经史、社会经济史、卫生史以及产科史等数据。结果 该研究共纳入200例绝经后患者,对其皮肤、毛发、指甲和口腔变化进行了评估。参与者的平均年龄为58.99±9.12岁。大多数参与者(n = 127,63.5%)的绝经起始年龄在40 - 50岁。按职业划分,大多数参与者是家庭主妇(n = 178,85.5%)。149例患者(74.5%)出现皱纹,这是常见的生理变化。在病理变化中,癣等真菌感染(n = 29,14.5%)最为常见。在湿疹性疾病中,9例患者(4.5%)出现的乏脂性湿疹最为常见;在丘疹鳞屑性疾病中,银屑病(n = 22,11%)最为常见。脂溢性角化病(n = 43,21.5%)是最常见的良性肿瘤;在精神皮肤疾病中,慢性单纯性苔藓(n = 3,1.5%)是最常遇到的疾病。结论 绝经后皮肤病是印度女性健康中一个重要但未得到充分认识的问题。本研究突出了萎缩性阴道炎、扁平苔藓和真菌感染等疾病在我国绝经后人群中的患病率。