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生殖系统及乳腺转移瘤——女童软组织和骨肉瘤转移瘤的叙述性综述及病例系列

The reproductive system and breast metastases - a narrative review and case series of metastases from soft tissue and bone sarcomas in girls.

作者信息

Sobieraj Paulina, Bilska Katarzyna, Bekiesinska-Figatowska Monika

机构信息

Department of Diagnostic Imaging, Institute of Mother and Child, Warsaw, Poland.

Department of Oncology and Surgical Oncology for Children and Youth, Institute of Mother and Child, Warsaw, Poland.

出版信息

Pol J Radiol. 2025 Feb 13;90:e84-e96. doi: 10.5114/pjr/200008. eCollection 2025.

Abstract

Four cases of girls with metastases of soft tissue or bone sarcomas to the reproductive system or breasts are reported. Two patients had metastases to the breast from rhabdomyosarcoma (RMS) of the limbs, one had metastases to the ovary from RMS of the foot, and one had metastases to the uterine venous plexus from chondrosarcoma of the sacrum. In each case, the appearance of metastases was shown in various imaging methods: ultrasound, magnetic resonance imaging, and computed tomography. A thorough literature review confirmed that only a few cases of soft tissue and bone sarcoma metastasis to the locations of primary interest of this article in girls have been described, especially in the context of reproductive organs. Despite the rare occurrence of this type of metastases, the malignant tumours mentioned above should be considered when differentiating the source. These rare clinical situations are woven into a review of malignant neoplasms' metastases to the reproductive organs and breast.

摘要

本文报告了4例软组织或骨肉瘤转移至生殖系统或乳房的女童病例。2例患者为肢体横纹肌肉瘤(RMS)转移至乳房,1例为足部RMS转移至卵巢,1例为骶骨软骨肉瘤转移至子宫静脉丛。在每例病例中,通过多种影像学方法(超声、磁共振成像和计算机断层扫描)显示了转移灶的情况。全面的文献回顾证实,仅有少数女童软组织和骨肉瘤转移至本文主要关注部位的病例被描述,尤其是在生殖器官方面。尽管这类转移罕见,但在鉴别来源时应考虑上述恶性肿瘤。这些罕见的临床情况被纳入对恶性肿瘤转移至生殖器官和乳房的综述中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e09/11973706/fb17f34087db/PJR-90-200008-g001.jpg

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