采用 MRI 对宫颈癌进行分期、复发和随访:FIGO 分期 2018 修订后欧洲泌尿生殖放射学会的更新指南。
Staging, recurrence and follow-up of uterine cervical cancer using MRI: Updated Guidelines of the European Society of Urogenital Radiology after revised FIGO staging 2018.
机构信息
Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Viale Regina Elena, 324 00161, Rome, Italy.
Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
出版信息
Eur Radiol. 2021 Oct;31(10):7802-7816. doi: 10.1007/s00330-020-07632-9. Epub 2021 Apr 14.
OBJECTIVES
The recommendations cover indications for MRI examination including acquisition planes, patient preparation, imaging protocol including multi-parametric approaches such as diffusion-weighted imaging (DWI-MR), dynamic contrast-enhanced imaging (DCE-MR) and standardised reporting. The document also underscores the value of whole-body 18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT) and highlights potential future methods.
METHODS
In 2019, the ESUR female pelvic imaging working group reviewed the revised 2018 FIGO staging system, the up-to-date clinical management guidelines, and the recent imaging literature. The RAND-UCLA Appropriateness Method (RAM) was followed to develop the current ESUR consensus guidelines following methodological steps: literature research, questionnaire developments, panel selection, survey, data extraction and analysis.
RESULTS
The updated ESUR guidelines are recommendations based on ≥ 80% consensus among experts. If ≥ 80% agreement was not reached, the action was indicated as optional.
CONCLUSIONS
The present ESUR guidelines focus on the main role of MRI in the initial staging, response monitoring and evaluation of disease recurrence. Whole-body FDG-PET plays an important role in the detection of lymph nodes (LNs) and distant metastases.
KEY POINTS
• T2WI and DWI-MR are now recommended for initial staging, monitoring of response and evaluation of recurrence. • DCE-MR is optional; its primary role remains in the research setting. • T2WI, DWI-MRI and whole-body FDG-PET/CT enable comprehensive assessment of treatment response and recurrence.
目的
本指南涵盖了 MRI 检查的适应证,包括采集平面、患者准备、成像方案,包括扩散加权成像(DWI-MRI)、动态对比增强成像(DCE-MRI)和标准化报告等多参数方法。本文还强调了全身 18-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG-PET/CT)的价值,并突出了潜在的未来方法。
方法
2019 年,ESUR 女性盆腔成像工作组审查了修订后的 2018 年 FIGO 分期系统、最新的临床管理指南和最近的影像学文献。采用 RAND-UCLA 适宜性方法(RAM),按照以下方法步骤制定了目前的 ESUR 共识指南:文献研究、问卷制定、专家小组选择、调查、数据提取和分析。
结果
更新后的 ESUR 指南是基于≥80%专家共识的推荐。如果未达成≥80%的共识,则表示该操作是可选的。
结论
目前的 ESUR 指南侧重于 MRI 在初始分期、反应监测和疾病复发评估中的主要作用。全身 FDG-PET 在检测淋巴结(LN)和远处转移方面发挥着重要作用。
要点
• T2WI 和 DWI-MRI 现在推荐用于初始分期、监测反应和评估复发。• DCE-MRI 是可选的,其主要作用仍在研究中。• T2WI、DWI-MRI 和全身 FDG-PET/CT 可全面评估治疗反应和复发。