Sardeshmukh Sadanand, Deshmukh Vineeta, Patil Tushar, Gujar Shweta, Godse Vasanti, Kulkarni Swapna, Datar Shrinivas, Deshpande Dhananjay, Sardeshmukh Nilambari, Bhuvad Sushma, Sardeshmukh Bhagyashree, Chavan Sandeep, Gupta Vidya
Bharatiya Sanskriti Darshan Trust's Integrated Cancer Treatment and Research Centre, Wagholi, Pune, Maharashtra, India.
Bharatiya Sanskriti Darshan Trust's Integrated Cancer Treatment and Research Centre, Wagholi, Pune, Maharashtra, India.
J Ayurveda Integr Med. 2025 Mar-Apr;16(2):101012. doi: 10.1016/j.jaim.2024.101012. Epub 2025 Apr 7.
Breast cancer is one of the major concerns in women globally. Treatment for breast cancer comprises surgery, chemotherapy, hormonal therapy, targeted therapy, and palliative care. Though chemotherapy is an important component of treatment, it induces adverse effects, which are mainly caused by the inability of chemotherapeutic drugs to distinguish between dividing cancer cells and normal cells leading to increase in oxidative stress and hampered immune status.
To investigate the benefits of Ayurvedic medicines in breast cancer patients for managing chemotherapy adverse effects.
In this retrospective study, 27 female breast cancer patients who underwent surgery, posted for chemotherapy, and complying inclusion were included. These patients were divided into two groups. Study group of 13 patients were treated with Ayurvedic formulation - Chemo-Recovery Kit with coral [filed as a herbo-mineral kit for Indian patent (201921018273- published) and US Patent (17/609,601- published)] along with chemotherapy, while 14 patients were not provided with any additional Ayurvedic medicines and were treated with chemotherapy alone (control group).
Out of commonly observed adverse effects, statistically significant improvement is noted in symptoms such as fatigue (p < 0.0001), vomiting (p = 0.001), nausea (p = 0.003) and skin discoloration (p = 0.005) in patients treated with adjunct Ayurvedic medicines. The remaining symptoms such as constipation, stomatitis and fever were also less prominent in this group. Karnofsky score (p < 0.0001) and quality of life assessed were well maintained in patients treated with Ayurvedic medicines.
Chemo-Recovery Kit with coral is highly effective in management of chemotherapy induced nausea, vomiting, fatigue and skin discoloration and thus to improve Quality of Life.
乳腺癌是全球女性主要关注的疾病之一。乳腺癌的治疗包括手术、化疗、激素治疗、靶向治疗和姑息治疗。尽管化疗是治疗的重要组成部分，但它会引发不良反应，主要是由于化疗药物无法区分正在分裂的癌细胞和正常细胞，导致氧化应激增加和免疫状态受损。
探讨阿育吠陀药物对乳腺癌患者化疗不良反应的管理益处。
在这项回顾性研究中，纳入了27例接受手术、准备进行化疗且符合纳入标准的女性乳腺癌患者。这些患者被分为两组。13例患者的研究组在化疗的同时接受阿育吠陀制剂——含珊瑚的化疗康复套装（作为草药-矿物质套装申请了印度专利（201921018273-已公布）和美国专利（17/609,601-已公布））治疗，而14例患者未接受任何额外的阿育吠陀药物，仅接受化疗（对照组）。
在常见的不良反应中，接受辅助阿育吠陀药物治疗的患者在疲劳（p<0.0001）、呕吐（p=0.001）、恶心（p=0.003）和皮肤变色（p=0.005）等症状方面有统计学意义的显著改善。该组的便秘、口腔炎和发热等其余症状也不那么突出。接受阿育吠陀药物治疗的患者的卡诺夫斯基评分（p<0.0001）和评估的生活质量得到了良好维持。
含珊瑚的化疗康复套装在管理化疗引起的恶心、呕吐、疲劳和皮肤变色方面非常有效，从而提高生活质量。
