Prieto-Callejero Blanca, Rivera Francisco, Fagundo-Rivera Javier, Romero Adolfo, Romero-Martín Macarena, Gómez-Salgado Juan, Ruiz-Frutos Carlos
Hospital Virgen de la Bella, Lepe, Huelva.
Department of Experimental Psychology, Faculty of Psychology, University of Seville, Seville.
Medicine (Baltimore). 2020 Aug 14;99(33):e21695. doi: 10.1097/MD.0000000000021695.
Chemotherapy does not only affect cancer cells; it also affects, to a greater or lesser degree, all other cells in the body. This toxicity should be assessed according to its severity, frequency, and duration, taking into account objective and subjective dimensions in its assessment. This assessment is a highly relevant aspect when providing care to chemotherapy patients, mainly due to the impact of the treatment on the patient's quality of life, as well as the vital risk it may imply under certain circumstances. For all this, the objective of this study was to assess the relationship between chemotherapy-associated adverse reactions and health-related quality of life in breast cancer patients.
With this purpose, a descriptive cross-sectional study was developed on 110 breast cancer patients who were treated with docetaxel, epirubicin, and cyclophosphamide.
It is worth highlighting the negative effect of nausea, dysgeusia, peripheral neuropathy, loss of appetite, myalgia, and peripheral edema on the quality of life. Likewise, it is worth mentioning peripheral neuropathy as the toxicity that affects a greater number of quality-of-life indicators.
To sum up, it would be necessary to make health professionals aware of the importance of chemotherapy-associated adverse reactions.
化疗不仅会影响癌细胞；它还会或多或少地影响体内所有其他细胞。这种毒性应根据其严重程度、发生频率和持续时间进行评估，评估时要考虑客观和主观方面。在为化疗患者提供护理时，这种评估是一个高度相关的方面，主要是因为治疗对患者生活质量的影响，以及在某些情况下可能意味着的生命风险。综上所述，本研究的目的是评估乳腺癌患者化疗相关不良反应与健康相关生活质量之间的关系。
为此，对110例接受多西他赛、表柔比星和环磷酰胺治疗的乳腺癌患者开展了一项描述性横断面研究。
值得强调的是，恶心、味觉障碍、周围神经病变、食欲不振、肌痛和周围水肿对生活质量有负面影响。同样，值得一提的是周围神经病变是影响更多生活质量指标的毒性反应。
总之，有必要让卫生专业人员意识到化疗相关不良反应的重要性。
