Tannier Xavier, Kalra Dipak
Sorbonne University, Inserm, University Sorbonne Paris-Nord, University Paris 13, Sorbonne Paris Cité, INSERM UMR_S 1142, LIMICS, F-75006 Paris, France.
The University of Gent, Gent, Belgium.
Yearb Med Inform. 2024 Aug;33(1):143-146. doi: 10.1055/s-0044-1800733. Epub 2025 Apr 8.
To summarize key contributions to current research in the field of Clinical Research Informatics (CRI) and to select the best papers published in 2023.
A bibliographic search using a combination of MeSH descriptors and free-text terms on CRI was performed using PubMed, followed by a double-blind review in order to select a list of candidate best papers to be then peer-reviewed by external reviewers. After peer-review ranking, a consensus meeting between the two section editors and the editorial team was organized to finally conclude on the selected three best papers.
Among the 1,119 papers returned by the search, published in 2023, that were in the scope of the various areas of CRI, the full review process selected three best papers. The first best paper describes the process undertaken in Germany, under the national Medical Informatics Initiative, to define and validate a provenance metadata framework to enable the interpretation including quality assessment of health data reused for research. The authors of the second-best paper present a methodology for the generation of computable phenotypes and the covariates associated with success rates in e-phenotype validation. The third-best presents a review of published and accessible tools that enable the assessment of health data quality through an automated process. This year's survey paper marks the tenth anniversary of the CRI section of the Yearbook by reviewing the dominant themes within CRI over the past decade and the major milestone innovations within this field.
The literature relevant to CRI in 2023 has largely been populated by publications that assess and enhance the reusability of health data for clinical research, in particular data quality assessment and metadata management.
总结对临床研究信息学（CRI）领域当前研究的关键贡献，并挑选2023年发表的最佳论文。
使用PubMed对CRI进行主题词表描述符和自由文本词组合的文献检索，随后进行双盲评审，以选出候选最佳论文列表，然后由外部评审员进行同行评审。在同行评审排名之后，组织了两位栏目编辑与编辑团队之间的共识会议，最终确定入选的三篇最佳论文。
在检索返回的2023年发表的、属于CRI各个领域范围内的1119篇论文中，整个评审过程选出了三篇最佳论文。第一篇最佳论文描述了在德国国家医学信息学倡议下所开展的过程，即定义和验证一个来源元数据框架，以实现对用于研究的健康数据的解释，包括质量评估。第二篇最佳论文的作者提出了一种生成可计算表型以及与电子表型验证成功率相关的协变量的方法。第三篇最佳论文对已发表且可获取的工具进行了综述，这些工具能够通过自动化过程评估健康数据质量。今年的综述论文通过回顾过去十年CRI领域的主导主题以及该领域的主要里程碑式创新，纪念了年鉴CRI栏目的十周年。
2023年与CRI相关的文献在很大程度上充斥着评估和提高健康数据在临床研究中的可重用性的出版物，特别是数据质量评估和元数据管理方面的出版物。
