Small G W, Matsuyama S S, Komanduri R, Kumar V, Jarvik L F
J Am Geriatr Soc. 1985 Aug;33(8):538-9. doi: 10.1111/j.1532-5415.1985.tb04617.x.
The authors compared the frequencies of prior thyroid disease, thyroid medication use, and abnormal serum thyroxine levels in 61 patients with dementia of the Alzheimer type (DAT) with those of 38 control subjects. They found that the 33 women with DAT had a 24.2% frequency of prior thyroid disease, comparable with that found in a previous epidemiologic study. The 19 female controls, however, had a similar frequency, failing to support a previously reported association between DAT and thyroid disease.
作者比较了61例阿尔茨海默型痴呆（DAT）患者和38例对照受试者既往甲状腺疾病的发生率、甲状腺药物使用情况以及血清甲状腺素水平异常情况。他们发现，33例患有DAT的女性既往甲状腺疾病发生率为24.2%，与之前一项流行病学研究的结果相当。然而，19名女性对照者的发生率与之相似，这并不支持之前报道的DAT与甲状腺疾病之间的关联。
