Touboul J P, Le Hoang P, Fontaine M, Wechsler B, Cabane J, Godeau P, Schuller E
J Fr Ophtalmol. 1985;8(4):321-31.
Syphilis is a well-established cause of uveal disease and is thought to be responsible for several distinct types of intraocular inflammation. Four cases of acquired syphilitic uveitis are reported. The diagnosis was essentially based on the clinical picture, the elimination of other possible causes, the results of reliable blood immunologic tests eg, the TPHA, FTA and Nelson tests, and the rapid response to penicillin therapy. Evaluation of anti-Treponema pallidum antibodies in the aqueous humor does not contribute to the diagnosis of syphilitic uveitis. Two cases needed large amounts of penicillin (total dosage, 440 million units). Oral steroids were used to control the associated inflammatory reaction and to prevent a Herxheimer reaction. All the patients responded well to therapy.
梅毒是葡萄膜疾病的一个既定病因，被认为是几种不同类型眼内炎症的病因。报告了4例后天性梅毒性葡萄膜炎病例。诊断主要基于临床表现、排除其他可能病因、可靠的血液免疫学检测结果（如梅毒螺旋体血凝试验、荧光密螺旋体抗体吸收试验和尼尔森试验）以及对青霉素治疗的快速反应。房水中抗梅毒螺旋体抗体的评估对梅毒性葡萄膜炎的诊断没有帮助。2例患者需要大量青霉素（总剂量4.4亿单位）。口服类固醇用于控制相关的炎症反应并预防赫克斯海默反应。所有患者对治疗反应良好。
