Ippoliti Elena, Falco Gennaro Marco, Di Giorgi Nicoletta, Lenkowitz Jacopo, Chiricozzi Andrea, Cannizzaro Maria Vittoria, Quattrini Laura, Caldarola Giacomo, De Simone Clara, D'Amore Alessandra, Peris Ketty
Dermatologia, Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy; Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Real World Data Facility, Gemelli Generator, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Acta Derm Venereol. 2025 Apr 8;105:adv42503. doi: 10.2340/actadv.v105.42503.
Despite the improvement of psoriasis treatment achieved with the use of biological therapies, some patients still require hospitalization. A retrospective study was conducted including patients affected by psoriasis hospitalized at Fondazione Policlinico Agostino Gemelli IRCCS in Rome, from 1 January 2012 to 1 August 2023, to describe the psoriasis patient journey. Of the 2.223 patients with psoriasis, 1,500 had it as the primary diagnosis. Some 93.2% (2,071/2,223) of patients were affected by plaque psoriasis, 4.8% (108/2,223) presented with erythrodermic psoriasis, and 2.0% (44/2,223) had generalized pustular psoriasis. 1,455/2,223 (65.5%) reported in their medical history psoriatic arthritis, and 771/2,223 (34.7%) hypertension; 328/2,223 (14.8%) psoriatic patients accessed the emergency department (ED), 291 of whom (13.1%) were subsequently hospitalized in different inpatient clinics, while 37 (1.6%) were then discharged. Inpatient clinic admission after ED was required more frequently in generalized pustular or erythrodermic psoriasis (47.7% and 38% respectively) compared with plaque psoriasis (11%). Patients admitted to an inpatient clinic after ED had a longer recovery compared with those admitted electively to an inpatient clinic (13.6 days vs 7.7 days, p < 0.001). Only 490/2,223 (20.9%) patients were admitted to a dermatology service. This study showed a shift in patient management rather than a reduction in hospitalizations.
尽管生物疗法在银屑病治疗方面取得了进展，但仍有一些患者需要住院治疗。进行了一项回顾性研究，纳入了2012年1月1日至2023年8月1日期间在罗马的圣心天主教大学综合医院（Fondazione Policlinico Agostino Gemelli IRCCS）住院的银屑病患者，以描述银屑病患者的就医过程。在2223例银屑病患者中，1500例以银屑病作为主要诊断。约93.2%（2071/2223）的患者为斑块状银屑病，4.8%（108/2223）为红皮病型银屑病，2.0%（44/2223）为泛发性脓疱型银屑病。2223例患者中有1455例（65.5%）有银屑病关节炎病史，771例（34.7%）有高血压病史；328例（14.8%）银屑病患者前往急诊科就诊，其中291例（13.1%）随后在不同的住院科室住院，37例（1.6%）随后出院。与斑块状银屑病（11%）相比，泛发性脓疱型或红皮病型银屑病患者在急诊科就诊后更频繁地需要住院科室收治（分别为47.7%和38%）。与择期入住住院科室的患者相比，急诊科就诊后入住住院科室的患者恢复时间更长（13.6天对7.7天，p<0.001）。只有490例（20.9%）患者入住皮肤科。这项研究表明患者管理方式发生了转变，而非住院人数减少。
