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本文引用的文献

1
Epidemiological Study of Canine Mast Cell Tumours According to the Histological Malignancy Grade.根据组织学恶性程度对犬肥大细胞瘤的流行病学研究
Pol J Vet Sci. 2017 Sep 26;20(3):455-465. doi: 10.1515/pjvs-2017-0055.
2
Antihistaminic and cardiorespiratory effects of diphenhydramine hydrochloride in anesthetized dogs undergoing excision of mast cell tumors.盐酸苯海拉明在接受肥大细胞瘤切除的麻醉犬中的抗组胺和心肺效应。
J Am Vet Med Assoc. 2017 Oct 1;251(7):804-813. doi: 10.2460/javma.251.7.804.
3
Cytologic comparison of the percentage of mast cells in lymph node aspirate samples from clinically normal dogs versus dogs with allergic dermatologic disease and dogs with cutaneous mast cell tumors.对临床正常犬、患有过敏性皮肤病的犬以及患有皮肤肥大细胞瘤的犬的淋巴结穿刺样本中肥大细胞百分比进行细胞学比较。
J Am Vet Med Assoc. 2017 Aug 15;251(4):421-428. doi: 10.2460/javma.251.4.421.
4
Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.金毛寻回犬全基因组关联研究确定了易患肥大细胞瘤的生殖系风险因素。
PLoS Genet. 2015 Nov 20;11(11):e1005647. doi: 10.1371/journal.pgen.1005647. eCollection 2015 Nov.
5
Surgically planned versus histologically measured lateral tumor margins for resection of cutaneous and subcutaneous mast cell tumors in dogs: 46 cases (2010-2013).犬皮肤和皮下肥大细胞瘤切除术中手术规划的与组织学测量的肿瘤外侧切缘:46例病例(2010 - 2013年)
J Am Vet Med Assoc. 2015 Jul 15;247(2):184-9. doi: 10.2460/javma.247.2.184.
6
A retrospective review of treatment and response of high-risk mast cell tumours in dogs.回顾性分析犬高危肥大细胞瘤的治疗及反应。
Vet Comp Oncol. 2016 Dec;14(4):361-370. doi: 10.1111/vco.12116. Epub 2014 Sep 15.
7
Evaluation of a modified proportional margins approach for surgical resection of mast cell tumors in dogs: 40 cases (2008-2012).犬肥大细胞瘤手术切除改良比例切缘方法的评估:40例病例(2008 - 2012年)
J Am Vet Med Assoc. 2013 Nov 15;243(10):1436-41. doi: 10.2460/javma.243.10.1436.
8
Breed-predispositions to cancer in pedigree dogs.纯种犬患癌的品种易感性。
ISRN Vet Sci. 2013 Jan 17;2013:941275. doi: 10.1155/2013/941275. Print 2013.
9
Validation of the prognostic value of histopathological grading or c-kit mutation in canine cutaneous mast cell tumours: a retrospective cohort study.验证组织病理学分级或 c-kit 突变在犬皮肤肥大细胞瘤预后中的价值:一项回顾性队列研究。
Vet J. 2013 Jun;196(3):492-8. doi: 10.1016/j.tvjl.2012.11.018. Epub 2013 Feb 4.
10
European consensus document on mast cell tumours in dogs and cats.《欧洲犬猫肥大细胞瘤共识文件》
Vet Comp Oncol. 2012 Sep;10(3):e1-e29. doi: 10.1111/j.1476-5829.2012.00341.x.

雌性犬外阴肥大细胞瘤切除术中的会阴切除术、部分阴道切除术及尿道成形术

Episiectomy and partial vaginectomy with urethroplasty for excision of vulvar mast cell tumour in a female dog.

作者信息

Dos Santos Daniele Lira, Chaves Jaese Farias, Souto Marcella Pinheiro, Lima Geyse Maria Machado, de Sousa Siqueira Julyanne, de Sousa Simon Silva, Silva Gabriele Sousa, Moura Marcio Alan Oliveira, Dos Santos Ribas Priscila, Schwanke Katiane, Junior Pedro Soares Bezerra, Teixeira Pedro Paulo Maia

机构信息

Veterinary Hospital, Federal University of Pará, Castanhal - Pará, Brazil.

Pathology Animal Lab, Federal University of Pará, Castanhal - Pará, Brazil.

出版信息

Vet Med (Praha). 2021 Mar 31;66(3):121-126. doi: 10.17221/94/2020-VETMED. eCollection 2021 Mar.

DOI:10.17221/94/2020-VETMED
PMID:40201431
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11975270/
Abstract

This case report describes the surgical treatment of a grade II mast cell tumour in the vulvar region of a 4-year-old female Miniature Pinscher dog. The patient weighed 2 kg, and the tumour measured 2 cm in diameter. The surgery involved an episiotomy, a partial vaginectomy, and a subsequent urethroplasty. Due to the patient's small size, the surgical margins were set at 2 cm laterally and 2 cm deep, which meant that the entire vulva, as well as the ventral part of the vaginal canal had to be removed. Afterwards, the urethral ostium was elliptically fixed to the skin at the end of the urethroplasty. The follow-up evaluations revealed an excellent recovery without metastasis or recurrence over the following two years.

摘要

本病例报告描述了一只4岁雌性迷你杜宾犬外阴区域二级肥大细胞瘤的手术治疗情况。该犬体重2千克,肿瘤直径2厘米。手术包括会阴切开术、部分阴道切除术及随后的尿道成形术。由于病犬体型小,手术切缘设定为外侧2厘米、深部2厘米,这意味着整个外阴以及阴道管腹侧部分都必须切除。之后,在尿道成形术结束时将尿道口椭圆形固定于皮肤。随访评估显示,在接下来的两年里恢复良好,无转移或复发。