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空洞性病变与胸腔积液:一例幼儿坏死性肺炎病例

Cavitary Lesions and Pleural Effusion: A Case of Necrotizing Pneumonia in a Young Child.

作者信息

Gujar Amrita A, Patel Aaska, Pierre Louisdon

机构信息

Pediatrics, The Brooklyn Hospital Center, Brooklyn, USA.

出版信息

Cureus. 2025 Mar 8;17(3):e80272. doi: 10.7759/cureus.80272. eCollection 2025 Mar.

Abstract

Necrotizing pneumonia is a rare and severe complication of bacterial pneumonia in children, characterized by cavitation and potential respiratory failure. A three-year-old child presented with fever, vomiting, and right-sided crackles on lung auscultation. Imaging revealed right upper lobe consolidation, and laboratory evaluation showed leukocytosis (WBC 29K), hyponatremia (Na 130 mEq/L), and elevated CRP (215.9 mg/L). Despite the use of intravenous antibiotics, the patient developed respiratory distress and required admission to the pediatric intensive care unit. Ultrasound revealed a loculated pleural effusion. The patient underwent video-assisted thoracic surgery with thoracotomy and chest tube placement. Cultures and acid-fast bacillus testing were negative, but pleural fluid analysis was consistent with exudative effusion. A CT scan revealed a cavitary lesion, confirming necrotizing pneumonia. He improved with antibiotics and surgical drainage and was discharged on a prolonged course of oral antibiotic regimen. Necrotizing pneumonia poses diagnostic challenges, particularly in cases with negative cultures. This case underscores the importance of a multimodal diagnostic approach, including imaging and pleural fluid analysis, to guide management. Multidisciplinary management, including antibiotics and surgical intervention, is critical for treating necrotizing pneumonia in pediatric patients.

摘要

坏死性肺炎是儿童细菌性肺炎一种罕见且严重的并发症,其特征为肺组织出现空洞及潜在的呼吸衰竭。一名三岁儿童出现发热、呕吐症状,肺部听诊右侧有啰音。影像学检查显示右上叶实变,实验室检查显示白细胞增多(白细胞计数29000)、低钠血症(血钠130 mEq/L)及C反应蛋白升高(215.9 mg/L)。尽管使用了静脉抗生素治疗,该患者仍出现呼吸窘迫,需入住儿科重症监护病房。超声检查发现有包裹性胸腔积液。患者接受了电视辅助胸腔镜手术,包括开胸及放置胸管。培养及抗酸杆菌检测均为阴性,但胸腔积液分析符合渗出性积液。CT扫描显示有空洞性病变,确诊为坏死性肺炎。经抗生素及手术引流治疗后病情好转,出院时接受了长时间的口服抗生素治疗。坏死性肺炎在诊断上存在挑战,尤其是在培养结果为阴性的病例中。该病例强调了采用包括影像学及胸腔积液分析在内的多模式诊断方法以指导治疗的重要性。多学科管理,包括使用抗生素及手术干预,对于治疗儿童坏死性肺炎至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/840f/11975787/1435a64c100e/cureus-0017-00000080272-i01.jpg

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