Karan Chand Mohan Singh Saravanasingh, I Nithyamala, Rajaraman Kaviyarasi, Balasubramanian Anbarasan, R Gayatri
Department of Maruthuvam (Siddha General Medicine), National Institute of Siddha, Chennai, IND.
Department of Siddha Pharmacology, National Institute of Siddha, Chennai, IND.
Cureus. 2025 Mar 9;17(3):e80281. doi: 10.7759/cureus.80281. eCollection 2025 Mar.
Cutaneous Larva Migrans (CLM) is a helminthic infection that is prevalent in tropical and subtropical regions. It is caused by zoonotic hookworms, predominantly the Ancylostoma species, which infrequently infect humans. Hookworms primarily inhabit the small intestine of canines and felines, where adult worms release eggs that are excreted in the host's feces into the environment. Human infections occur through direct contact with contaminated soil, with humans serving as dead-end hosts for parasites. Clinically, CLM presents as erythematous, serpiginous, and intensely pruritic cutaneous eruptions caused by penetration and migration of larvae. Although the infection is generally confined to the skin, rare instances of larval migration to the lungs can result in more severe complications. A 71-year-old male presented with a progressive, curvilinear, erythematous track in the left upper quadrant region of the abdomen, accompanied by intense pruritus, a burning sensation, and a localized nodular lesion. Erythema was observed approximately 3-4 cm from the site of larval penetration, with the serpiginous tract extending approximately 10 cm in length. The diagnosis of cutaneous larva migrans (CLM) was established based on the characteristic clinical presentation. The Siddha herbal formulation Naakupoochi Kudineer was administered 60 ml twice after meals for seven days, resulting in gradually reducing symptoms and resolving the tract over the following weeks. This study highlights the safety and effectiveness of a Siddha herbal formulation in the treatment of CLM.
皮肤幼虫移行症(CLM)是一种在热带和亚热带地区流行的蠕虫感染。它由人畜共患的钩虫引起,主要是钩口线虫属物种,这些钩虫很少感染人类。钩虫主要寄生于犬科和猫科动物的小肠,成虫在那里产卵,卵随宿主粪便排出到环境中。人类通过直接接触受污染的土壤而感染,人类是寄生虫的终末宿主。临床上,CLM表现为由幼虫穿透和移行引起的红斑、匐行性和剧烈瘙痒的皮肤疹。虽然感染通常局限于皮肤,但幼虫罕见地迁移到肺部可导致更严重的并发症。一名71岁男性患者,在左上腹区域出现一条进行性、曲线状、红斑性轨迹,伴有剧烈瘙痒、烧灼感和局部结节性病变。在距幼虫穿透部位约3 - 4厘米处观察到红斑,匐行性轨迹长度约为10厘米。根据特征性临床表现确诊为皮肤幼虫移行症(CLM)。给予悉达草药配方Naakupoochi Kudineer,饭后服用60毫升,每日两次,共服用七天,症状逐渐减轻,在接下来的几周内轨迹消退。本研究强调了悉达草药配方在治疗CLM方面的安全性和有效性。