Kambhampati Srinivas B S, Rajagopalan Senthilvelan, Abraham Vineet Thomas, Poduval Murali, Maini Lalit
Sri Dhaatri Orthopaedic, Maternity and Gynaecology Center, SKDGOC, Vijayawada, Andhra Pradesh 531127 India.
Department of Shoulder and Upper Limb Surgery, MIOT International, Chennai, 600089 India.
Indian J Orthop. 2024 Dec 2;59(3):280-293. doi: 10.1007/s43465-024-01295-0. eCollection 2025 Mar.
Osteoporosis, characterised by decreased bone mass and degradation of bone tissue, poses a major global health concern, particularly for the ageing population. The traditional fixation techniques often fail in osteoporotic bones due to their diminished density and strength. Technological advancements in orthopaedic implants, specifically nails, plates, and external fixators, have emerged to address these challenges.
Improvements in implant design focus on material properties, surface modifications, and geometric advancements. Titanium and its alloys are favoured for their biomechanical properties such as lower elastic modulus and high strength-to-weight ratio. The biodegradable materials like polylactic acid and magnesium alloys offer the advantage of gradual resorption as bone heals. Surface modifications, such as coatings with bioactive materials and drug-eluting surfaces, promote osseointegration and enhance fixation strength.
Intramedullary (IM) nails have evolved to enhance stability and minimise complications associated with osteoporotic fractures. Third and fourth-generation nails incorporate surface treatments for better integration and healing. The advances in screw design, locking mechanisms, and flexible axial stimulation have improved fixation and allowed micromotion, which promotes fracture healing. The use of external fixators, particularly for complex fractures in osteoporotic bones, offers less invasive treatment options with adaptable stiffness for improved healing.
Technological innovations in implant materials, design, and surgical techniques have significantly improved the management of osteoporotic fractures. Newer technologies, including 3D printing, virtual and augmented reality, and artificial intelligence, show promise in enhancing implant customization, surgical planning, and postoperative outcomes. However, further clinical validation and research are needed to expand their clinical applications.
骨质疏松症以骨量减少和骨组织退化为特征,是一个重大的全球健康问题,对老年人群体尤为如此。由于骨质疏松性骨的密度和强度降低,传统的固定技术常常失效。骨科植入物,特别是髓内钉、钢板和外固定器,在技术上取得了进展以应对这些挑战。
植入物设计的改进集中在材料特性、表面改性和几何形状改进方面。钛及其合金因其较低的弹性模量和高强度重量比等生物力学特性而受到青睐。聚乳酸和镁合金等可生物降解材料具有随着骨愈合而逐渐吸收的优势。表面改性,如用生物活性材料涂层和药物洗脱表面,可促进骨整合并增强固定强度。
髓内钉已经发展到增强稳定性并将与骨质疏松性骨折相关的并发症降至最低。第三代和第四代髓内钉采用表面处理以实现更好的整合和愈合。螺钉设计、锁定机制和柔性轴向刺激方面的进展改善了固定并允许微动,从而促进骨折愈合。外固定器的使用,特别是用于骨质疏松性骨的复杂骨折,提供了侵入性较小的治疗选择,其刚度可调节以促进愈合。
植入物材料、设计和手术技术方面的技术创新显著改善了骨质疏松性骨折的治疗。包括3D打印、虚拟现实和增强现实以及人工智能在内的新技术在增强植入物定制、手术规划和术后结果方面显示出前景。然而,需要进一步的临床验证和研究以扩大其临床应用。