Kitagawa H
Nihon Sanka Fujinka Gakkai Zasshi. 1985 Jun;37(6):964-72.
A method for the continuous recording of uteroplacental blood flow (PBF) in late pregnancies by using 99mTc-albumin has been described. The PBF curve of toxemia of pregnancy has been plotted to indicate small artery spasm in proving ischemic necrosis of placenta. In the PBF of placental insufficiency evidenced by the values for urinary E3, an unfavorable build-up and a delayed build-up time were observed. The pathologic diagnosis showed condensation, fusion and necrosis of villi. In the PBF in which a intrauterine fetal death (IUFD) was caused by placental factors, a sudden change in the PBF was observed showing the presence of an ischemia. In the PBF of pregnancy with diabetes, a large wave pattern change was observed indicating a decrease in the PBF. The pathologic diagnosis showed the fusion, hyalinization and necrosis of villi. The PBF wave patterns were classified into four kinds: normal pattern, angio-spasm pattern, delayed build-up pattern, circulation pattern. It has become clear that these abnormal wave patterns are frequently observed in toxemia of pregnancy, placental insufficiency and pregnancy with diabetes.
已经描述了一种使用99mTc - 白蛋白连续记录晚期妊娠子宫胎盘血流（PBF）的方法。绘制了妊娠中毒症的PBF曲线，以表明小动脉痉挛，从而证明胎盘缺血性坏死。在以尿E3值为证据的胎盘功能不全的PBF中，观察到不良的上升和延迟的上升时间。病理诊断显示绒毛有浓缩、融合和坏死。在由胎盘因素导致宫内胎儿死亡（IUFD）的PBF中，观察到PBF突然变化，表明存在缺血。在糖尿病妊娠的PBF中，观察到大波型变化，表明PBF降低。病理诊断显示绒毛有融合、玻璃样变和坏死。PBF波形分为四种类型：正常型、血管痉挛型、延迟上升型、循环型。很明显，这些异常波形在妊娠中毒症、胎盘功能不全和糖尿病妊娠中经常观察到。
