Maashi M, Elkhodary H, Bamashmous N, Felemban O, Alamoudi N
Ministry of Health, Jeddah, Saudi Arabia.
Pediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University, P.O. Box 80200, 21589, Jeddah, Saudi Arabia.
Eur Arch Paediatr Dent. 2025 Apr 9. doi: 10.1007/s40368-025-01030-9.
The concept of Chemomechanical Caries Removal (CMCR) includes the selective removal of caries-infected tissue while preserving caries-affected tissue. However, studies examining its application to children are scarce. The aim was to assess pain perception and time duration of CMCR agents when removing caries in primary molars in a sample of children compared to the conventional method of caries removal using rotary burs.
A randomized controlled clinical trial with a split-mouth design with a sample of 60 children aged 4-9 years with 120 cavitated occlusal carious primary molars was equally distributed into 2 experiments: BRIX3000 vs. conventional method (Experiment 1) and Carie-Care™ vs. conventional method (Experiment 2). The time duration of caries removal was recorded. Perception of pain during caries excavation was evaluated using the "Wong-Baker FACES Pain Rating Scale."
Caries removal using the conventional method was significantly faster compared to CMCR agents in both experiments (P < 0.001 and P < 0.001). Caries removal using BRIX3000 was significantly faster than Carie-Care™ (P < 0.001). Caries removal with BRIX3000 or Carie-Care™ were reported less painful than the conventional method (P = 0.002 and P = 0.011, respectively).
The study concluded that although CMCR methods require more time for caries removal, they were reported to be less painful.
The study protocol was registered at www.
gov under the identifier NCT05427591.
化学机械性龋损去除（CMCR）的概念包括在保留受龋影响组织的同时选择性去除感染龋的组织。然而，研究其在儿童中的应用的研究很少。目的是评估与使用旋转车针的传统龋损去除方法相比，CMCR制剂在去除儿童样本中乳磨牙龋损时的疼痛感知和持续时间。
一项采用口内对照设计的随机对照临床试验，样本为60名4至9岁的儿童，有120颗咬合面龋坏的乳磨牙，平均分为2个试验：BRIX3000与传统方法（试验1）以及Carie-Care™与传统方法（试验2）。记录龋损去除的持续时间。使用“面部表情疼痛评分量表”评估龋洞预备过程中的疼痛感知。
在两个试验中，使用传统方法去除龋损均明显比CMCR制剂更快（P < 0.001和P < 0.001）。使用BRIX3000去除龋损明显比Carie-Care™更快（P < 0.001）。据报告，使用BRIX3000或Carie-Care™去除龋损比传统方法疼痛程度更低（分别为P = 0.002和P = 0.011）。
该研究得出结论，虽然CMCR方法去除龋损需要更多时间，但据报告其疼痛程度更低。
