Fathalla Hussein, Ghoneim Mohamed Adel, Katatny Amr El
Division of Neurosurgery, Cairo University Hospitals, Cairo, Egypt.
Neurosurg Rev. 2025 Apr 10;48(1):356. doi: 10.1007/s10143-025-03474-5.
The current recommended treatment for NPH is insertion of a programmable shunt. In developing countries however, this might sometimes not be feasible due to cost and logistical reasons. Patients in rural areas are required to travel hundreds of miles for frequent follow-up visits for reprogramming, rendering the treatment protocol troublesome and sometimes even not possible. Our approach was to treat these patients with standard gravitational shunts (MIETKE GAV) instead of programmable shunts and assess the outcome. 43 cases were treated by the authors from the period of 2018 to 2023. Only patients classified as probable NPH according to the INPH guidelines criteria were included. We used fixed pressure non-programmable gravitational shunts for all patients. Improvement was assessed using the Krauss method and only patients with 50% improvement or more were considered improved. There were 33 males and 10 females with a mean age was 74 years. Initially only 30 (69.7%) improved however, after a second surgery for 7 of the remaining 13 patients, the final number of improved patients were 35 (81.3%). Median follow up was 23 months. The use of fixed pressure gravitational shunts such as the GAV shunt, is a good second option for treating NPH patients in developing countries and rural communities. This approach provides a cheap, reliable, and practical solution for NPH patients living in rural areas, without the need for frequent follow-up visits. Although long-term follow-up is still needed, the success rate so far is satisfactory.
目前推荐的正常压力脑积水(NPH)治疗方法是插入可编程分流器。然而,在发展中国家,由于成本和后勤原因,有时这可能不可行。农村地区的患者需要跋涉数百英里进行频繁的重新编程随访,这使得治疗方案麻烦,有时甚至无法实施。我们的方法是用标准重力分流器(MIETKE GAV)而非可编程分流器治疗这些患者并评估结果。作者在2018年至2023年期间治疗了43例患者。仅纳入根据正常压力脑积水指南标准分类为可能患有NPH的患者。我们对所有患者使用固定压力不可编程重力分流器。使用克劳斯方法评估改善情况,只有改善50%或更多的患者才被视为有所改善。有33名男性和10名女性,平均年龄为74岁。最初只有30名(69.7%)患者有所改善,然而,在对其余13名患者中的7名进行第二次手术后,改善患者的最终数量为35名(81.3%)。中位随访时间为23个月。使用诸如GAV分流器之类的固定压力重力分流器,对于发展中国家和农村社区的NPH患者来说是一个很好的第二选择。这种方法为生活在农村地区的NPH患者提供了一种廉价、可靠且实用的解决方案,无需频繁随访。尽管仍需要长期随访,但到目前为止成功率令人满意。