Heisenberg M, Borst A, Wagner S, Byers D
J Neurogenet. 1985 Feb;2(1):1-30. doi: 10.3109/01677068509100140.
Two Drosophila mutants are described in which the connections between the input to and the output from the mushroom bodies is largely interrupted. In all forms of the flies (larva, imago, male, female) showing the structural defect, olfactory conditioning is impaired. Learning is completely abolished when electroshock is used as reinforcement and partially suppressed in reward learning with sucrose. No influence of the mushroom body defect on the perception of the conditioning stimuli or on spontaneous olfactory behavior is observed. The defect seems not to impair learning of color discrimination tasks or operant learning involving visual cues.
描述了两种果蝇突变体，其中蘑菇体的输入和输出之间的连接在很大程度上被中断。在所有表现出结构缺陷的果蝇形态（幼虫、成虫、雄性、雌性）中，嗅觉条件反射都受到损害。当使用电击作为强化手段时，学习完全被消除，而在蔗糖奖励学习中则部分受到抑制。未观察到蘑菇体缺陷对条件刺激的感知或自发嗅觉行为有影响。该缺陷似乎不会损害颜色辨别任务的学习或涉及视觉线索的操作性学习。
