β地中海贫血患者的视力会恶化到什么程度？一例病例报告及文献综述。
How bad can vision get in beta-thalassemia? A case report and review of the literature.
作者信息
Azimi Ali, Zia Zahra
机构信息
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Ophthalmology, Jahrom University of Medical Sciences, Jahrom, I. R. of Iran.
出版信息
BMC Ophthalmol. 2025 Apr 9;25(1):189. doi: 10.1186/s12886-025-04028-5.
BACKGROUND
Review various causes of optic disc-related decreased vision and present a rare anterior ischemic optic neuropathy (AION) case in a patient with beta-thalassemia.
CASE PRESENTATION
A 38-year-old man with a known case of major beta-thalassemia presented with a chief complaint of acute decrease in central and peripheral vision in the right eye. The patient was on deferoxamine and had previous splenectomy surgery. Fundus examination revealed visible vascular obstruction, more prominent superior disc swelling, hyperemia, and retinal nerve fiber layer (RNFL) edema in the right eye. After 6 months, the visual acuity improved in the follow-up examination, and the fundus examination revealed subtle right disc pallor.
CONCLUSION
AION with visible vascular occlusion can be a rare retinal cause of acute decreased vision in beta-thalassemia patients.
背景
回顾各种与视盘相关的视力下降原因，并介绍一例β地中海贫血患者罕见的前部缺血性视神经病变（AION）病例。
病例报告
一名38岁男性，已知患有重度β地中海贫血，主诉右眼中心和周边视力急性下降。该患者正在接受去铁胺治疗，此前已接受脾切除术。眼底检查发现右眼可见血管阻塞，视盘上半肿胀、充血更明显，视网膜神经纤维层（RNFL）水肿。6个月后，随访检查视力有所改善，眼底检查发现右眼视盘轻度苍白。
结论
伴有可见血管阻塞的AION可能是β地中海贫血患者急性视力下降的一种罕见视网膜病因。
Zotero 插件