Peter Chloé, Antonietti Evelyne, Antoniou Maria-Paraskevi, Bucaille Elvire, Osório Joana Almeida, Manificat Sabine, Rodríguez-Herreros Borja, Chabane Nadia
Autism Spectrum Disorders Service, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Ann N Y Acad Sci. 2025 May;1547(1):143-153. doi: 10.1111/nyas.15320. Epub 2025 Apr 10.
Autism spectrum disorder (ASD) is a neurodevelopmental condition that significantly affects children's development, posing a significant challenge in pediatric healthcare. Early parent-mediated interventions (PMIs) aim to improve a child's social communication skills through joint engagement in daily activities. However, widespread access to this type of intervention is heavily limited due to implementation barriers and logistical challenges. The use of technology may offer promising alternatives to reach more families. This randomized controlled trial will assess the efficacy of an innovative e-coaching program designed to provide parents of young children with ASD with effective strategies via an online learning platform combined with personalized debriefings. It will compare e-coaching to standard Pediatric Autism Communication Therapy and to the absence of a PMI, with all three arms combined with community assistance as usual, in a cohort of 99 families with preschool children with ASD. The primary outcome will be the quality of parent-child interaction, measured through behavioral assessments and simultaneous dual gaze recording with head-mounted eye-tracking during semi-structured standardized play sessions. Secondary outcomes will include the child's developmental level and parental well-being. If validated, e-coaching could be disseminated to reach more families and have a positive impact on their quality of life.
自闭症谱系障碍(ASD)是一种神经发育疾病,严重影响儿童发育,给儿科医疗保健带来重大挑战。早期家长介导干预(PMI)旨在通过共同参与日常活动来提高儿童的社交沟通技能。然而,由于实施障碍和后勤挑战,这类干预措施的广泛普及受到严重限制。利用技术可能提供有前景的替代方案,以惠及更多家庭。这项随机对照试验将评估一项创新的电子辅导计划的效果,该计划旨在通过在线学习平台结合个性化汇报,为患有ASD的幼儿家长提供有效策略。在99个有学龄前ASD儿童的家庭组成的队列中,将电子辅导与标准的儿科自闭症沟通治疗以及不进行PMI进行比较,所有三组都照常结合社区援助。主要结果将是亲子互动质量,通过行为评估以及在半结构化标准化游戏环节中使用头戴式眼动追踪同步记录双眼注视情况来衡量。次要结果将包括儿童的发育水平和家长的幸福感。如果得到验证,电子辅导可以推广以惠及更多家庭,并对他们的生活质量产生积极影响。