Fujiwara Shotaro, Ishida Takuto, Mizuno Masafumi
Department of Psychiatry Tokyo Metropolitan Matsuzawa Hospital Tokyo Japan.
Department of Internal Medicine Tokyo Metropolitan Matsuzawa Hospital Tokyo Japan.
PCN Rep. 2025 Apr 8;4(2):e70093. doi: 10.1002/pcn5.70093. eCollection 2025 Jun.
Screening laboratory tests for patients with acute psychiatric symptoms are discouraged in general emergency services but are recommended by emergency psychiatric guidelines due to the high prevalence of abnormal findings in severe psychiatric patients. The present study aimed to evaluate the utility of screening laboratory tests in a real-world, emergency psychiatric setting through focusing on how often abnormal values lead to medical interventions.
The electronic medical records were reviewed for adult patients who were involuntarily admitted to Tokyo Metropolitan Matsuzawa Hospital for an imminent risk of self-harm or harm to others between October 2019 and September 2022. The number of patients, abnormal screening laboratory findings, and medical interventions were examined.
Of the 600 patients identified in the review, 595 had abnormal laboratory findings, but only 97 (16.3%) underwent medical interventions related to these results. Frequently observed abnormal findings, such as elevated creatine kinase and an elevated white blood cell count, were often attributed to the patient's agitation or were considered clinically nonsignificant. Notably, one-third of the interventions prompted by laboratory findings resulted only in additional testing. More than half of the treatments were either of questionable necessity or nonurgent. Medical interventions other than additional tests were more likely to be prompted by the patient's medical history and presentation.
In the emergency psychiatric setting, abnormal laboratory findings are common, but clinical decisions largely rely on the patient's medical history and presentation, with few requiring immediate interventions. A history-driven approach may enhance the clinical value of laboratory tests.
一般急诊服务不鼓励对有急性精神症状的患者进行实验室筛查,但由于重症精神病患者异常检查结果的高发生率,急诊精神科指南推荐进行此类筛查。本研究旨在通过关注异常值导致医疗干预的频率,评估在现实世界的急诊精神科环境中筛查实验室检查的效用。
回顾了2019年10月至2022年9月期间因有立即自伤或伤害他人风险而被非自愿收治入东京都松泽医院的成年患者的电子病历。检查了患者数量、异常的实验室筛查结果以及医疗干预情况。
在回顾中确定的600例患者中,595例有异常的实验室检查结果,但只有97例(16.3%)接受了与这些结果相关的医疗干预。经常观察到的异常结果,如肌酸激酶升高和白细胞计数升高,往往归因于患者的激动情绪或被认为在临床上无显著意义。值得注意的是,由实验室检查结果引发的干预中有三分之一仅导致了进一步的检查。超过一半的治疗要么必要性存疑,要么并不紧急。除进一步检查外的医疗干预更有可能由患者的病史和临床表现引发。
在急诊精神科环境中,异常的实验室检查结果很常见,但临床决策很大程度上依赖于患者的病史和临床表现,很少需要立即干预。以病史为导向的方法可能会提高实验室检查的临床价值。