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生物充填：一种使用牙髓生物材料进行根管治疗的新方法。

Bio-obturation: A Novel Approach in Root Canal Treatment Using Endodontic Biomaterials.

作者信息

Asgary Saeed

机构信息

Iranian Center for Endodontic Research, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Iran Endod J. 2025;20(1):e15. doi: 10.22037/iej.v20i1.47630. Epub 2025 Feb 19.

DOI:10.22037/iej.v20i1.47630
PMID:40206780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11980999/
Abstract

Bio-obturation is an innovative approach in root canal therapy that effectively addresses complex clinical challenges using bioactive endodontic materials. This report highlights 14 diverse cases where bio-obturation was employed to manage complications such as internal and external resorption, root perforations, draining sinus tracts, mechanical obstructions, and trauma-related injuries. The outcomes demonstrate notable healing and resolution of various tooth related pathologies in failed primary root canal treatments. Root perforations and canal blockages were successfully sealed, restoring the integrity of the root canal system and ensuring continued tooth function and retention. Bio-obturation facilitated stabilization and regeneration of periradicular and supporting tissues in trauma cases, including avulsed teeth and inflammatory root resorption. Cases involving open apices, dens invaginatus, and complex root canal anatomy also showed favorable results. Overall, bio-obturation offers a transformative alternative to conventional root canal filling by promoting enhanced biological sealing and improved periradicular healing, thus increasing the probability of sustainable long-term clinical success. While calcium-enriched mixture cement served as the bioactive material in these cases, this approach may also be effectively implemented using other advanced calcium silicate-based biomaterials, broadening its applicability in challenging endodontic scenarios.

摘要

生物性根管充填是根管治疗中的一种创新方法，它使用生物活性牙髓材料有效应对复杂的临床挑战。本报告重点介绍了14个不同病例，其中采用生物性根管充填来处理诸如内吸收和外吸收、根管穿孔、引流窦道、机械性阻塞以及与创伤相关的损伤等并发症。结果显示，在失败的乳牙根管治疗中，各种与牙齿相关的病理状况得到了显著愈合和缓解。根管穿孔和根管阻塞成功封闭，恢复了根管系统的完整性，确保牙齿功能持续并得以保留。在创伤病例中，包括牙齿脱位和炎性牙根吸收，生物性根管充填促进了根尖周组织和支持组织的稳定与再生。涉及开放根尖、牙内陷和复杂根管解剖结构的病例也显示出良好效果。总体而言，生物性根管充填通过促进更强的生物封闭性和改善根尖周愈合，为传统根管充填提供了一种变革性替代方法，从而提高了长期临床可持续成功的概率。虽然在这些病例中富钙混合水泥作为生物活性材料，但该方法也可使用其他先进的硅酸钙基生物材料有效实施，从而扩大其在具有挑战性的牙髓治疗场景中的适用性。

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2
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Biomed Eng Online. 2024 Sep 18;23(1):96. doi: 10.1186/s12938-024-01290-4.
3
Reprint of: The Effect of Mineral Trioxide Aggregate Obturation Levels on the Outcome of Endodontic Retreatment: An Observational Study.
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Iran Endod J. 2025;20(1):e19. doi: 10.22037/iej.v20i1.46885. Epub 2025 Mar 11.
矿化三氧化物凝聚体（MTA）充填水平对根管再治疗效果的影响：一项观察性研究。
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