Magadum Ajit
Aging and Cardiovascular Discovery Center (ACDC), Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Center for Regenerative Medicine and USF Health Heart Institute, Department of Internal Medicine, University of South Florida, Tampa, FL 33602, USA.
Extracell Vesicles Circ Nucl Acids. 2025 Mar 25;6(1):180-182. doi: 10.20517/evcna.2024.81. eCollection 2025.
A recent study introduces Stem Cell-derived Exosome Nebulization Therapy (SCENT), a novel, non-invasive strategy that delivers lung spheroid cell-derived exosomes via inhalation to promote cardiac repair after myocardial infarction. This approach improves cardiac function, reduces injury, and demonstrates translational potential in both small and large animal models, offering a promising avenue for cell-free, inhalable regenerative therapies.
最近的一项研究引入了干细胞衍生外泌体雾化疗法（SCENT），这是一种新型的非侵入性策略，通过吸入递送肺球状体细胞衍生的外泌体，以促进心肌梗死后的心脏修复。这种方法可改善心脏功能，减少损伤，并在小型和大型动物模型中都显示出转化潜力，为无细胞、可吸入的再生疗法提供了一条有前景的途径。
