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上睑“低脂”真皮内梭形细胞脂肪瘤:一例报告

"Low-fat" intradermal spindle cell lipoma of the upper eyelid: a case report.

作者信息

Wilson Mary Kate, Goldberg Elizabeth, Fantin Aldo, Erdag Gulsun

机构信息

Department of Ophthalmology, University of Florida, Gainesville, Florida.

North Florida / South Georgia Veterans Health System, Gainesville, Florida.

出版信息

Digit J Ophthalmol. 2024 Dec 31;30(4):70-74. doi: 10.5693/djo.02.2024.06.005. eCollection 2024.

DOI:10.5693/djo.02.2024.06.005
PMID:40207302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11977295/
Abstract

Spindle cell lipomas are slow-growing, benign tumors composed of bland spindle cells, adipocytes, and collagen bundles. They are typically found on the posterior neck, shoulder, or upper back. Spindle cell lipomas represent only a small percentage of reported lipomatous tumor types. We report the case of a 90-year-old white man who presented with a solid mobile lesion on his right upper eyelid. Histopathological and immunohistochemical analysis of the lesion led to a diagnosis of a "low-fat," intradermal, spindle cell lipoma. This case underscores the importance of considering spindle cell lipoma in the differential diagnosis for atypical eyelid lesions.

摘要

梭形细胞脂肪瘤是一种生长缓慢的良性肿瘤,由形态温和的梭形细胞、脂肪细胞和胶原束组成。它们通常出现在后颈部、肩部或上背部。梭形细胞脂肪瘤在已报道的脂肪瘤类型中仅占一小部分。我们报告了一例90岁白人男性患者,其右上眼睑出现一个实性可移动肿物。对该肿物进行组织病理学和免疫组化分析后诊断为“低脂”型真皮内梭形细胞脂肪瘤。该病例强调了在非典型眼睑病变的鉴别诊断中考虑梭形细胞脂肪瘤的重要性。

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本文引用的文献

1
Spindle Cell Lipoma and Pleomorphic Lipoma: An Update and Review.梭形细胞脂肪瘤和多形性脂肪瘤:最新进展与综述
Cancer Diagn Progn. 2023 May 3;3(3):282-290. doi: 10.21873/cdp.10213. eCollection 2023 May-Jun.
2
Mammary-type myofibroblastoma with infarction and atypical mitosis-a potential diagnostic pitfall: A case report.伴有梗死和非典型有丝分裂的乳腺型肌纤维母细胞瘤——一个潜在的诊断陷阱:病例报告
World J Clin Cases. 2022 Jun 6;10(16):5343-5351. doi: 10.12998/wjcc.v10.i16.5343.
3
The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior.孤立性纤维瘤的多面性;组织学特征的多样性、鉴别诊断以及分子研究和替代标志物在避免误诊和预测行为中的作用。
Diagn Pathol. 2021 Apr 20;16(1):32. doi: 10.1186/s13000-021-01095-2.
4
Dermatofibrosarcoma Protuberans.隆突性皮肤纤维肉瘤。
Dermatol Clin. 2019 Oct;37(4):483-488. doi: 10.1016/j.det.2019.05.006.
5
Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum.非典型梭形细胞脂肪瘤样肿瘤:232例形态谱病例的临床病理特征
Am J Surg Pathol. 2017 Feb;41(2):234-244. doi: 10.1097/PAS.0000000000000770.
6
Spindle Cell Lipomas Arising at Atypical Locations.非典型部位发生的梭形细胞脂肪瘤
Am J Clin Pathol. 2016 Oct;146(4):487-95. doi: 10.1093/ajcp/aqw137.
7
Mammary-Type Myofibroblastoma: A Report of Two Cases.乳腺型肌纤维母细胞瘤:2例报告
J Pathol Transl Med. 2016 Sep;50(5):385-9. doi: 10.4132/jptm.2016.03.26. Epub 2016 Jun 6.
8
Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.罕见肿瘤,罕见部位:一种基于真皮的梭形细胞/多形性脂肪瘤。
Am J Dermatopathol. 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546.
9
Mammary-type Myofibroblastoma: Clinicopathologic Characterization in a Series of 143 Cases.乳腺型肌纤维母细胞瘤:143例病例系列的临床病理特征
Am J Surg Pathol. 2016 Mar;40(3):361-7. doi: 10.1097/PAS.0000000000000540.
10
"Low Fat" Spindle Cell Lipoma of the Eyelid: A Diagnostic Challenge.眼睑“低脂”梭形细胞脂肪瘤:一项诊断挑战。
Ophthalmic Plast Reconstr Surg. 2017 May/Jun;33(3S Suppl 1):S49-S51. doi: 10.1097/IOP.0000000000000492.