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使用干式关节镜通过微骨折和全关节镜自体基质诱导软骨形成治疗膝关节局灶性软骨缺损

Focal Knee Cartilage Defect Treatment With Nanofracture and All-Arthroscopic Autologous Matrix-Induced Chondrogenesis Using Dry Arthroscopy.

作者信息

Wan Joseph Jon-Yin, Loh James Sir-Young

机构信息

Department of Orthopaedic Surgery, Changi General Hospital, Singapore.

出版信息

Arthrosc Tech. 2024 Oct 16;14(3):103272. doi: 10.1016/j.eats.2024.103272. eCollection 2025 Mar.

DOI:10.1016/j.eats.2024.103272
PMID:40207331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11977127/
Abstract

Autologous matrix-induced chondrogenesis (AMIC) combined with nanofracture had been shown to produce superior results in treating knee defects and has become increasingly popular. This technique can be achieved via open surgery or arthroscopy. The technical challenges to arthroscopic implantation of the scaffold include compromise of the operative view by soft tissue and fluid, difficult scaffold delivery through the portal, or scaffold damage. Carbon dioxide (CO) insufflation and special equipment have been reported to facilitate scaffold implantation with favorable outcomes. The authors describe their technique of scaffold implantation with a slotted cannula and a dissector through an enlarged working portal with no CO insufflation. Effective implantation of the scaffold is made possible through attention to soft tissue, equalization of the air pressure within and outside the joint, and the unique geometry of readily available instruments in the orthopaedic operating theatre.

摘要

自体基质诱导软骨形成(AMIC)联合微骨折术已被证明在治疗膝关节缺损方面效果更佳,且越来越受欢迎。该技术可通过开放手术或关节镜手术实现。关节镜下植入支架的技术挑战包括软组织和液体对手术视野的影响、通过入口困难地输送支架或支架损坏。据报道,二氧化碳(CO)充气和特殊设备有助于支架植入并取得良好效果。作者描述了他们通过扩大的工作入口,使用带槽套管和剥离器在不进行CO充气的情况下植入支架的技术。通过关注软组织、平衡关节内外气压以及利用骨科手术室中现有器械的独特几何形状,实现支架的有效植入成为可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/d8d5248959de/gr9.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/f79a78b53833/gr4.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/a32dda47b3bd/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/6dd161f1c0be/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/d8d5248959de/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/452deadb7d2a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/d2e43644fa73/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/80982be98a0a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/f79a78b53833/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/9d3ed02341fb/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/d9c1b0b4aa5c/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/a32dda47b3bd/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/6dd161f1c0be/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d431/11977127/d8d5248959de/gr9.jpg

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本文引用的文献

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Arthroscopy versus mini-arthrotomy approach for matrix-induced autologous chondrocyte implantation in the knee: a systematic review.关节镜与小切口关节切开术治疗膝关节基质诱导自体软骨细胞移植的比较:系统评价。
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一种使用低成本、易获取的套管辅助膝关节干关节镜软骨修复中支架植入的技术。
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